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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Irag1
inositol 1,4,5-triphosphate receptor associated 1
MGI:1338023
38 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Irag1em1(IMPC)Ccpcz/Irag1em1(IMPC)Ccpcz
C57BL/6NCrl-Irag1em1(IMPC)Ccpcz/Ccpcz 		abnormal cecum morphology J:211773
abnormal heart morphology J:211773
abnormal liver morphology J:211773
abnormal seminal vesicle morphology J:211773
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
decreased circulating alkaline phosphatase level J:211773
decreased circulating serum albumin level J:211773
decreased erythrocyte cell number J:211773
decreased hemoglobin content J:211773
decreased lean body mass J:211773
decreased lymphocyte cell number J:211773
enlarged cecum J:211773
enlarged liver J:211773
enlarged spleen J:211773
increased eosinophil cell number J:211773
increased fasting circulating glucose level J:211773
increased freezing behavior J:211773
increased mean corpuscular hemoglobin J:211773
increased mean corpuscular volume J:211773
increased neutrophil cell number J:211773
increased red blood cell distribution width J:211773
increased spleen weight J:211773
increased total body fat amount J:211773
small heart J:211773
small seminal vesicle J:211773
thrombocytosis J:211773
Irag1tm1Jens/Irag1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		impaired smooth muscle contractility J:94387
Irag1tm1Jens/Irag1tm1Jens
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal intestinal transit time J:94387
decreased heart rate J:94387
decreased systemic arterial blood pressure J:94387
gastric hypertrophy J:94387
impaired smooth muscle contractility J:94387
premature death J:94387
pyloric stenosis J:94387
Irag1tm2.1Jens/Irag1tm2.1Jens
involves: 129S1/Sv * 129X1/SvJ 		abnormal digestive system morphology J:175887
abnormal systemic arterial blood pressure J:175887
abnormal vascular smooth muscle physiology J:175887
impaired muscle relaxation J:175887
premature death J:175887
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory