Rnd2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rnd2
Rho family GTPase 2
MGI:1338755

23 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rnd2^em1(IMPC)Mbp/Rnd2^em1(IMPC)Mbp C57BL/6NCrl-Rnd2^em1(IMPC)Mbp/Mmucd	abnormal heart morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal pancreas morphology	J:211773
	abnormal seminal vesicle morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal urinary bladder morphology	J:211773
	enlarged heart	J:211773
	enlarged seminal vesicle	J:211773
	enlarged spleen	J:211773
	enlarged urinary bladder	J:211773
	increased body length	J:211773
	prolonged RR interval	J:211773
Rnd2^tm1.1Fgu/Rnd2^tm1.1Fgu Not Specified	abnormal action potential	J:344858
	abnormal cerebellar granule cell migration	J:344858
	abnormal dendrite arborization pattern	J:344858
	abnormal hippocampus neuron morphology	J:344858
	normal behavior/neurological phenotype	J:344858
	increased anxiety-related response	J:344858
	increased neuron apoptosis	J:344858
Rnd2^tm1.1Jya/Rnd2^tm1.1Jya Tg(Mbp-cre)9Gvn/0 involves: C57BL/6 * FVB/N	abnormal myelination	J:309719
	decreased myelin sheath thickness	J:309719
	increased myelin sheath thickness	J:309719
Rnd2^tm1.1Jya/Rnd2^tm1.1Jya Tg(Plp1-cre/ERT)3Pop/0 B6.Cg-Rnd2^tm1.1Jya Tg(Plp1-cre/ERT)3Pop	abnormal myelination	J:309719
	decreased myelin sheath thickness	J:309719
	increased myelin sheath thickness	J:309719

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/05/2024 MGI 6.24