Rnd2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rnd2
Rho family GTPase 2
MGI:1338755

21 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rnd2^em1(IMPC)Mbp/Rnd2^em1(IMPC)Mbp C57BL/6NCrl-Rnd2^em1(IMPC)Mbp/Mmucd	abnormal liver morphology	J:211773
	abnormal pancreas morphology	J:211773
	abnormal seminal vesicle morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal urinary bladder morphology	J:211773
	anophthalmia	J:211773
	enlarged spleen	J:211773
	enlarged urinary bladder	J:211773
	increased body length	J:211773
	prolonged RR interval	J:211773
Rnd2^tm1.1Fgu/Rnd2^tm1.1Fgu Not Specified	abnormal action potential	J:344858
	abnormal cerebellar granule cell migration	J:344858
	abnormal dendrite arborization pattern	J:344858
	abnormal hippocampus neuron morphology	J:344858
	normal behavior/neurological phenotype	J:344858
	increased anxiety-related response	J:344858
	increased neuron apoptosis	J:344858
Rnd2^tm1.1Jya/Rnd2^tm1.1Jya Tg(Mbp-cre)9Gvn/0 involves: C57BL/6 * FVB/N	abnormal myelination	J:309719
	decreased myelin sheath thickness	J:309719
	increased myelin sheath thickness	J:309719
Rnd2^tm1.1Jya/Rnd2^tm1.1Jya Tg(Plp1-cre/ERT)3Pop/0 B6.Cg-Rnd2^tm1.1Jya Tg(Plp1-cre/ERT)3Pop	abnormal myelination	J:309719
	decreased myelin sheath thickness	J:309719
	increased myelin sheath thickness	J:309719

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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