Cyfip1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cyfip1
cytoplasmic FMR1 interacting protein 1
MGI:1338801

14 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cyfip1^Gt(XG769)Byg/Cyfip1^Gt(XG769)Byg involves: 129P2/OlaHsd * C57BL/6	abnormal rostral-caudal body axis extension	J:163586
	delayed somite formation	J:163586
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:163586
	impaired somite development	J:163586
	kinked neural tube	J:163586
	open neural tube	J:163586
Cyfip1^l7Rl1-2R/Cyfip1^l7Rl1-2R Mixed stock	abnormal rostral-caudal body axis extension	J:163586
	delayed somite formation	J:163586
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:163586
	impaired somite development	J:163586
	kinked neural tube	J:163586
	open neural tube	J:163586
	prenatal lethality, complete penetrance	J:100221
Cyfip1^l7Rl1-3R/Cyfip1^l7Rl1-3R Mixed stock	abnormal rostral-caudal body axis extension	J:163586
	delayed somite formation	J:163586
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:163586
	impaired somite development	J:163586
	kinked neural tube	J:163586
	open neural tube	J:163586
	prenatal lethality, complete penetrance	J:100221
Cyfip1^tm1Yhj/Cyfip1⁺ B6J.129S7-Cyfip1^tm1Yhj	abnormal anxiety-related response	J:229098
	abnormal CNS synaptic transmission	J:229098
	abnormal long-term depression	J:229098
	decreased locomotor activity	J:229098
	enhanced cued conditioning behavior	J:229098
	enhanced paired-pulse facilitation	J:229098
Cyfip1^tm1Yhj/Cyfip1^tm1Yhj B6J.129S7-Cyfip1^tm1Yhj	embryonic lethality, complete penetrance	J:229098

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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