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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
MGI:1338889
30 phenotypes from 3 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Uhrf1tm1a(EUCOMM)Wtsi/Uhrf1+
Not Specified 		abnormal gait J:165965
decreased body weight J:165965
increased NK cell number J:165965
Uhrf1tm1Hko/Uhrf1tm1Hko
Not Specified 		abnormal allantois morphology J:129097
abnormal DNA methylation J:129097
abnormal mesoderm development J:129097
abnormal nervous system morphology J:129097
abnormal neural tube closure J:129097
abnormal sclerotome morphology J:129097
embryonic growth arrest J:129097
embryonic growth retardation J:129097
embryonic lethality during organogenesis, complete penetrance J:129097
small pharyngeal arch J:129097
Uhrf1tm1Smoc/Uhrf1tm1Smoc
Tg(Amh-cre)8815Reb/0
involves: C57BL/6J * FVB/N 		abnormal cell cycle J:324178
abnormal DNA methylation J:324178
abnormal Sertoli cell barrier function J:324178
abnormal Sertoli cell barrier morphology J:324178
abnormal Sertoli cell development J:324178
abnormal Sertoli cell morphology J:324178
arrest of spermatogenesis J:324178
decreased male germ cell number J:324178
decreased Sertoli cell number J:324178
decreased Sertoli cell proliferation J:324178
decreased testis weight J:324178
ectopic Sertoli cells J:324178
increased male germ cell apoptosis J:324178
male infertility J:324178
seminiferous tubule degeneration J:324178
small epididymis J:324178
small seminiferous tubules J:324178
small testis J:324178
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory