S100a1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

S100a1
S100 calcium binding protein A1
MGI:1338917

25 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
S100a1^em1(IMPC)Mbp/S100a1^em1(IMPC)Mbp C57BL/6NCrl-S100a1^em1(IMPC)Mbp/MbpMmucd	abnormal auditory brainstem response	J:211773
	abnormal eye morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal vitreous body morphology	J:211773
	anophthalmia	J:211773
	cataract	J:211773
	enlarged testis	J:211773
	small testis	J:211773
S100a1^{Gt(OST24588)Lex}/S100a1^{Gt(OST24588)Lex} involves: 129S5/SvEvBrd * C57BL/6J	no abnormal phenotype detected	J:103485
S100a1^{Gt(OST28275)Lex}/S100a1^{Gt(OST28275)Lex} involves: 129S5/SvEvBrd * C57BL/6	abnormal emotion/affect behavior	J:117944
	abnormal response to novel object	J:117944
	decreased anxiety-related response	J:117944
	increased exploration in new environment	J:117944
S100a1^tm1Jhh/S100a1⁺ involves: 129S1/Sv * C57BL/6	decreased cardiac muscle contractility	J:75781
S100a1^tm1Jhh/S100a1^tm1Jhh involves: 129S1/Sv * C57BL/6	abnormal lung endothelial cell physiology	J:230300
	abnormal lung vasculature morphology	J:230300
	abnormal nitric oxide homeostasis	J:230300
	decreased cardiac muscle contractility	J:75781
	decreased vasodilation	J:230300
	increased heart right ventricle weight	J:230300
	increased left ventricle systolic pressure	J:230300
	increased lung endothelial cell apoptosis	J:230300
	increased pulmonary vascular resistance	J:230300
	increased right ventricle systolic pressure	J:230300
	pulmonary hypertension	J:230300
S100a1^tm1Mfs/S100a1^tm1Mfs involves: 129S6/SvEvTac * C57BL/6	abnormal muscle physiology	J:132177

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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