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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		S1pr3
sphingosine-1-phosphate receptor 3
MGI:1339365
16 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
S1pr3tm1.1Hrose/S1pr3tm1.1Hrose
B6.Cg-S1pr3tm1.1Hrose 		no abnormal phenotype detected J:227542
S1pr3tm1b(EUCOMM)Wtsi/S1pr3tm1b(EUCOMM)Wtsi
C57BL/6N-S1pr3tm1b(EUCOMM)Wtsi/Bay 		abnormal retina blood vessel morphology J:211773
abnormal retina morphology J:211773
abnormal skin coloration J:211773
female infertility J:211773
male infertility J:211773
S1pr3tm1Jch/S1pr3tm1Jch
involves: 129S1/Sv * 129X1/SvJ 		abnormal cytokine level J:133917
decreased susceptibility to endotoxin shock J:133917
decreased susceptibility to induced morbidity/mortality J:133917
enlarged mesenteric lymph nodes J:133917
S1pr3tm1Jch/S1pr3tm1Jch
involves: 129S1/Sv * 129X1/SvJ * C57BL/6N 		abnormal cell physiology J:71372
abnormal pulmonary alveolus epithelial cell morphology J:99867
decreased litter size J:71372
normal hearing/vestibular/ear phenotype J:118369
S1pr3tm1Rlp/S1pr3tm1Rlp
involves: 129S6/SvEvTac * C57BL/6 		abnormal B cell physiology J:91161
normal cardiovascular system phenotype J:106055
normal hearing/vestibular/ear phenotype J:121165
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory