Pak3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pak3
p21 (RAC1) activated kinase 3
MGI:1339656

15 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pak3^tm1.1Rpo/Y B6.129S2(Cg)-Pak3^tm1.1Rpo	abnormal dentate gyrus neuron dendrite morphology	J:292116
	abnormal learning/memory/conditioning	J:292116
	abnormal long-term spatial reference memory	J:292116
	abnormal neuron differentiation	J:292116
	abnormal neuron physiology	J:292116
Pak3^tm1Zpj/Pak3^tm1Zpj either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * CD-1)	abnormal conditioned taste aversion behavior	J:99811
	reduced long-term potentiation	J:99811
Tg(Camk2a-AIDPak)21Stl/0 C57BL/6-Tg(Camk2a-AIDPak)21Stl	abnormal dendritic spine morphology	J:90763
	abnormal long-term spatial reference memory	J:90763
	abnormal miniature excitatory postsynaptic currents	J:90763
	abnormal synapse morphology	J:90763
	abnormal synaptic vesicle number	J:90763
	enhanced long-term potentiation	J:90763
	impaired contextual conditioning behavior	J:90763
	normal nervous system phenotype	J:90763
	reduced long-term depression	J:90763

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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