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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Csf2rb
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
MGI:1339759
20 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Csf2rbtm1Clsc/Csf2rbtm1Clsc
Csf2rb2tm1Cgb/Csf2rb2tm1Cgb
C.129S1-Csf2rb2tm1Cgb Csf2rbtm1Clsc 		abnormal dendritic cell physiology J:130939
abnormal interleukin secretion J:130939
abnormal plasmacytoid dendritic cell physiology J:130939
abnormal T cell activation J:130939
abnormal T cell physiology J:130939
decreased airway responsiveness J:130939
decreased interleukin-4 secretion J:130939
decreased interleukin-5 secretion J:130939
decreased interleukin-13 secretion J:130939
decreased susceptibility to type I hypersensitivity reaction J:130939
decreased T cell proliferation J:130939
impaired eosinophil recruitment J:130939
increased IgG1 level J:130939
lymph node hyperplasia J:130939
Csf2rbtm1Clsc/Csf2rbtm1Clsc
Csf2rb2tm1Cgb/Csf2rb2tm1Cgb
involves: 129S1/Sv 		abnormal bone marrow cell number J:109889
Csf2rbtm1Mur/Csf2rbtm1Mur
Il3tm1Tyb/Il3tm1Tyb
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 		abnormal eosinophil physiology J:35829
abnormal myeloblast morphology/development J:35829
abnormal pulmonary alveolus morphology J:35829
decreased eosinophil cell number J:35829
lung inflammation J:35829
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory