Mettl1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mettl1
methyltransferase 1, tRNA methylguanosine
MGI:1339986

24 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Mettl1^em1Bcgen/Mettl1^em1Bcgen Tg(Prrx1-cre)1Cjt/0 involves: C57BL/6J * SJL/J	abnormal bone ossification	J:355649
	abnormal cell physiology	J:355649
	abnormal cellular respiration	J:355649
	abnormal chondrocyte morphology	J:355649
	abnormal endochondral bone ossification	J:355649
	abnormal mitochondrial physiology	J:355649
	abnormal osteoblast morphology	J:355649
	abnormal trabecular bone morphology	J:355649
	decreased body size	J:355649
	decreased bone mineral density of femur	J:355649
	decreased bone mineralization	J:355649
	decreased bone ossification	J:355649
	decreased bone trabecula number	J:355649
	decreased cellular glucose uptake	J:355649
	decreased chondrocyte proliferation	J:355649
	decreased trabecular bone thickness	J:355649
	decreased trabecular bone volume	J:355649
	decreased width of hypertrophic chondrocyte zone	J:355649
	increased bone trabecular spacing	J:355649
	increased cellular ATP level	J:355649
	increased oxygen consumption	J:355649
	short femur	J:355649
	short humerus	J:355649
	short limbs	J:355649

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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