Mmp13 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mmp13
matrix metallopeptidase 13
MGI:1340026

22 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mmp13^{em1(IMPC)Ccpcz}/Mmp13^{em1(IMPC)Ccpcz} C57BL/6NCrl-Mmp13^{em1(IMPC)Ccpcz}/Ccpcz	abnormal spleen morphology	J:211773
	abnormal thymus morphology	J:211773
	decreased heart rate	J:211773
	enlarged spleen	J:211773
	enlarged thymus	J:211773
	increased circulating alkaline phosphatase level	J:211773
	prolonged QT interval	J:211773
	prolonged RR interval	J:211773
	short tibia	J:211773
Mmp13^tm1.1Werb/Mmp13^tm1.1Werb involves: 129S2/SvPas	abnormal trabecular bone morphology	J:94460
Mmp13^tm1.1Werb/Mmp13^tm1.1Werb involves: 129S2/SvPas	increased width of hypertrophic chondrocyte zone	J:94460
Mmp13^tm1Jdar/Mmp13^tm1Jdar B6.129S-Mmp13^tm1Jdar	decreased angiogenesis	J:150790
	decreased cell proliferation	J:150790
	delayed wound healing	J:150790
Mmp13^tm1Jdar/Mmp13^tm1Jdar involves: 129S/SvEv * C57BL/6J	abnormal bone healing	J:120352
	abnormal cartilage development	J:120352
	decreased angiogenesis	J:120352
Mmp13^tm1Smk/Mmp13^tm1Smk involves: 129S4/SvJae * C57BL/6	abnormal long bone hypertrophic chondrocyte zone	J:94723
	delayed bone ossification	J:94723
	increased long bone epiphyseal plate size	J:94723
	increased trabecular bone mass	J:94723
	short femur	J:94723
Mmp13^tm1Werb/Mmp13^tm1Werb Tg(CMV-cre)1Cgn/0 involves: 129S2/SvPas * BALB/cJ * C57BL/6	normal integument phenotype	J:104953
Mmp13^tm1Werb/Mmp13^tm1Werb Tg(Col1a1-cre)1Kry/0 involves: 129S2/SvPas	abnormal trabecular bone morphology	J:94460
Mmp13^tm1Werb/Mmp13^tm1Werb Tg(Col2a1-cre)1Rsjo/0 involves: 129S2/SvPas	abnormal trabecular bone morphology	J:94460
	increased width of hypertrophic chondrocyte zone	J:94460

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24