Sgk1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sgk1
serum/glucocorticoid regulated kinase 1
MGI:1340062

8 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sgk1^tm1.2Palm/Sgk1^tm1.2Palm 129/Sv-Sgk1^tm1.2Palm	increased circulating aldosterone level	J:148648
	increased urine potassium level	J:148648
	increased urine sodium level	J:148648
Sgk1^tm1Kuhl/Sgk1^tm1Kuhl either: (involves: 129/Sv * C57BL/6) or (involves: 129/Sv * 129X1/SvJ)	abnormal renal sodium ion transport	J:80115
	decreased renal glomerular filtration rate	J:80115
	increased circulating aldosterone level	J:80115
	increased susceptibility to weight loss	J:80115
Sgk1^tm1Kuhl/Sgk1^tm1Kuhl involves: 129S1/Sv * 129X1/SvJ	decreased susceptibility to hypertension	J:291559
Sgk1^tm1Kuhl/Sgk1^tm1Kuhl involves: 129S1/Sv * 129X1/SvJ	decreased susceptibility to induced morbidity/mortality	J:291559

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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