Fkbp8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fkbp8
FK506 binding protein 8
MGI:1341070

39 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fkbp8^{Gt(OST287985)Lex}/Fkbp8^{Gt(OST287985)Lex} involves: 129S5/SvEvBrd * C57BL/6	abnormal dorsal-ventral axis patterning	J:132031
	abnormal neural tube morphology	J:132031
	abnormal spinal cord morphology	J:132031
	abnormal vertebral arch development	J:132031
	disorganized dorsal root ganglion	J:132031
	hindlimb paralysis	J:132031
	increased neural tube apoptosis	J:132031
	increased spinal cord size	J:132031
	short vertebral column	J:132031
	slow postnatal weight gain	J:132031
	spina bifida	J:132031
	vertebral fusion	J:132031
Fkbp8^tm1Kei/Fkbp8^tm1Kei involves: 129P2/OlaHsd	abnormal cell physiology	J:132541
Fkbp8^tm1Kei/Fkbp8^tm1Kei involves: 129P2/OlaHsd * C57BL/6J	abnormal brain morphology	J:132961
	abnormal cerebellum morphology	J:132961
	abnormal cerebral hemisphere morphology	J:132961
	abnormal dorsal root ganglion morphology	J:132961
	abnormal embryonic neuroepithelium morphology	J:132961
	abnormal embryonic/fetal subventricular zone morphology	J:132961
	abnormal limb morphology	J:132961
	abnormal lumbar vertebrae morphology	J:132961
	abnormal neural tube morphology	J:132961
	abnormal neuron differentiation	J:132961
	abnormal rib morphology	J:132961
	abnormal spinal cord morphology	J:132961
	abnormal suckling behavior	J:132961
	abnormal thalamus morphology	J:132961
	abnormal vertebral arch morphology	J:132961
	clubfoot	J:132961
	curly tail	J:132961
	cyanosis	J:132961
	decreased body size	J:132961
	dehydration	J:132961
	exencephaly	J:132961
	neonatal lethality, complete penetrance	J:132961
	respiratory distress	J:132961
	scoliosis	J:132961
	spina bifida	J:132961
Fkbp8^tm1Tili/Fkbp8^tm1Tili involves: C57BL/6	abnormal dorsal-ventral axis patterning	J:89364
	abnormal neural tube morphology	J:89364
	anophthalmia	J:89364
	embryonic lethality during organogenesis, complete penetrance	J:89364
	microphthalmia	J:89364
	small dorsal root ganglion	J:89364
Fkbp8^tm1Tili/Fkbp8^tm1Tili Not Specified	embryonic lethality during organogenesis, complete penetrance	J:132961

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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