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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
MGI:1341087
36 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tnksem1(IMPC)Hmgu/Tnksem1(IMPC)Hmgu
C57BL/6N-Tnksem1(IMPC)Hmgu/Ieg 		abnormal bone structure J:211773
abnormal retina morphology J:211773
decreased bone mineral content J:211773
decreased bone mineral density J:211773
decreased circulating cholesterol level J:211773
decreased circulating glucose level J:211773
decreased circulating HDL cholesterol level J:211773
decreased circulating triglyceride level J:211773
decreased erythrocyte cell number J:211773
decreased grip strength J:211773
decreased total body fat amount J:211773
decreased total retina thickness J:211773
hydrocephaly J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating aspartate transaminase level J:211773
increased circulating bilirubin level J:211773
increased fasting circulating glucose level J:211773
increased heart weight J:211773
increased lean body mass J:211773
increased mean platelet volume J:211773
increased red blood cell distribution width J:211773
thrombocytopenia J:211773
TnksGt(RRC239)Byg/TnksGt(RRC239)Byg
involves: 129P2/OlaHsd * C57BL/6 		decreased circulating leptin level J:154388
decreased epididymal fat pad weight J:154388
decreased renal fat pad weight J:154388
hypoglycemia J:154388
increased adiponectin level J:154388
increased body temperature J:154388
increased circulating insulin level J:154388
increased circulating ketone body level J:154388
increased food intake J:154388
increased muscle cell glucose uptake J:154388
increased oxygen consumption J:154388
Tnkstm1.1Yjc/Tnkstm1.1Yjc
involves: 129S1/Sv * FVB/N 		normal cellular phenotype J:137985
normal growth/size/body region phenotype J:137985
normal homeostasis/metabolism phenotype J:137985
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory