Tnfrsf10b Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tnfrsf10b
tumor necrosis factor receptor superfamily, member 10b
MGI:1341090

13 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tnfrsf10b^tm1.1Cjk/Tnfrsf10b^tm1.1Cjk involves: 129P2/OlaHsd * BALB/c * NIH/OlaHsd	increased metastatic potential	J:130806
Tnfrsf10b^tm1Wnt/Tnfrsf10b^tm1Wnt involves: 129S6/SvEvTac * C57BL/6	abnormal innate immunity	J:94681
	abnormal interferon level	J:94681
	decreased susceptibility to Herpesvirales infection	J:94681
	decreased susceptibility to Herpesvirales infection induced morbidity/mortality	J:94681
	increased circulating interferon-gamma level	J:94681
	increased circulating interleukin-12b level	J:94681
	increased interleukin-12 secretion	J:94681
	increased NK cell number	J:94681
	increased tumor necrosis factor secretion	J:94681
Tnfrsf10b^tm1Wsed/Tnfrsf10b^tm1Wsed involves: 129P2/OlaHsd	decreased cellular sensitivity to gamma-irradiation	J:96816
	decreased physiological sensitivity to xenobiotic	J:96816
	enlarged thymus	J:96816

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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