Rp1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rp1
retinitis pigmentosa 1 (human)
MGI:1341105

23 phenotypes from 7 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rp1^m1Jdun/Rp1^m1Jdun C57BL/6-Rp1^m1Jdun	abnormal photoreceptor outer segment morphology	J:214837
	abnormal retina photoreceptor morphology	J:214837
	decreased a-wave amplitude	J:214837
	decreased b-wave amplitude	J:214837
	disorganized photoreceptor inner segment	J:214837
	disorganized photoreceptor outer segment	J:214837
	retina photoreceptor degeneration	J:214837
	retina rod cell degeneration	J:214837
	short photoreceptor inner segment	J:214837
	short photoreceptor outer segment	J:214837
	thin retina outer nuclear layer	J:214837
Rp1^tm1Eap/Rp1⁺ involves: 129S6/SvEvTac * C57BL/6	abnormal cone electrophysiology	J:85754
Rp1^tm1Eap/Rp1⁺ involves: 129S6/SvEvTac * C57BL/6	abnormal rod electrophysiology	J:85754
Rp1^tm1Eap/Rp1^tm1Eap involves: 129S6/SvEvTac	abnormal photoreceptor outer segment morphology	J:109781
Rp1^tm1Eap/Rp1^tm1Eap involves: 129S6/SvEvTac	abnormal retina photoreceptor morphology	J:109781
Rp1^tm1Eap/Rp1^tm1Eap involves: 129S6/SvEvTac * C57BL/6	abnormal cone electrophysiology	J:85754
	abnormal photoreceptor outer segment morphology	J:85754
	abnormal rod electrophysiology	J:85754
	increased susceptibility to age-related retinal degeneration	J:85754
	thin retina outer nuclear layer	J:85754
Rp1^tm1Jnz/Rp1⁺ involves: 129S7/SvEvBrd	abnormal rod electrophysiology	J:151463
Rp1^tm1Jnz/Rp1^tm1Eap involves: 129S6/SvEvTac * 129S7/SvEvBrd	abnormal photoreceptor outer segment morphology	J:109781
Rp1^tm1Jnz/Rp1^tm1Jnz involves: 129S7/SvEvBrd	abnormal eye physiology	J:76071
	abnormal ocular fundus morphology	J:76071
	abnormal photoreceptor outer segment morphology	J:76071, J:109781
	abnormal retina photoreceptor morphology	J:76071
	abnormal rod electrophysiology	J:151463
	decreased retina photoreceptor cell number	J:76071
	retina cone cell degeneration	J:76071
Rp1^tm2.1Eap/Rp1^tm2.1Eap involves: 129S7/SvEvBrd	abnormal cone electrophysiology	J:191685
	abnormal eye electrophysiology	J:191685
	abnormal photoreceptor outer segment morphology	J:191685
	abnormal retina neuronal layer morphology	J:191685
	abnormal rod electrophysiology	J:191685
	thin retina outer nuclear layer	J:191685
Rp1^tm2.1Eap/Rp1^tm2.1Eap Tg(Rp1)L2Eap/0 involves: 129S7/SvEvBrd * C57BL/6	abnormal retina neuronal layer morphology	J:191685
	abnormal rod electrophysiology	J:191685
	retina degeneration	J:191685
	short photoreceptor outer segment	J:191685
Rp1^tm2.1Eap/Rp1^tm2.1Eap Tg(Rp1)T1Eap/0 involves: 129S7/SvEvBrd * C57BL/6	abnormal cone electrophysiology	J:191685
	abnormal rod electrophysiology	J:191685
	normal vision/eye phenotype	J:191685
Rp1^tvrm64/Rp1^tvrm64 C57BL/6J-Rp1^tvrm64/J	abnormal ocular fundus morphology	J:166679
	abnormal retina vasculature morphology	J:166679
	retina photoreceptor degeneration	J:166679
	short photoreceptor inner segment	J:166679
	short photoreceptor outer segment	J:166679
	normal vision/eye phenotype	J:166679
Tg(Rp1)L2Eap/0 involves: C57BL/6	normal vision/eye phenotype	J:191685
Tg(Rp1)T1Eap/0 involves: C57BL/6	normal vision/eye phenotype	J:191685

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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