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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rp1
retinitis pigmentosa 1 (human)
MGI:1341105
23 phenotypes from 7 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Rp1m1Jdun/Rp1m1Jdun
C57BL/6-Rp1m1Jdun 		abnormal photoreceptor outer segment morphology J:214837
abnormal retina photoreceptor morphology J:214837
decreased a-wave amplitude J:214837
decreased b-wave amplitude J:214837
disorganized photoreceptor inner segment J:214837
disorganized photoreceptor outer segment J:214837
retina photoreceptor degeneration J:214837
retina rod cell degeneration J:214837
short photoreceptor inner segment J:214837
short photoreceptor outer segment J:214837
thin retina outer nuclear layer J:214837
Rp1tm1Eap/Rp1+
involves: 129S6/SvEvTac * C57BL/6 		abnormal cone electrophysiology J:85754
abnormal rod electrophysiology J:85754
Rp1tm1Eap/Rp1tm1Eap
involves: 129S6/SvEvTac 		abnormal photoreceptor outer segment morphology J:109781
abnormal retina photoreceptor morphology J:109781
Rp1tm1Eap/Rp1tm1Eap
involves: 129S6/SvEvTac * C57BL/6 		abnormal cone electrophysiology J:85754
abnormal photoreceptor outer segment morphology J:85754
abnormal rod electrophysiology J:85754
increased susceptibility to age-related retinal degeneration J:85754
thin retina outer nuclear layer J:85754
Rp1tm1Jnz/Rp1+
involves: 129S7/SvEvBrd 		abnormal rod electrophysiology J:151463
Rp1tm1Jnz/Rp1tm1Eap
involves: 129S6/SvEvTac * 129S7/SvEvBrd 		abnormal photoreceptor outer segment morphology J:109781
Rp1tm1Jnz/Rp1tm1Jnz
involves: 129S7/SvEvBrd 		abnormal eye physiology J:76071
abnormal ocular fundus morphology J:76071
abnormal photoreceptor outer segment morphology J:76071, J:109781
abnormal retina photoreceptor morphology J:76071
abnormal rod electrophysiology J:151463
decreased retina photoreceptor cell number J:76071
retina cone cell degeneration J:76071
Rp1tm2.1Eap/Rp1tm2.1Eap
involves: 129S7/SvEvBrd 		abnormal cone electrophysiology J:191685
abnormal eye electrophysiology J:191685
abnormal photoreceptor outer segment morphology J:191685
abnormal retina neuronal layer morphology J:191685
abnormal rod electrophysiology J:191685
thin retina outer nuclear layer J:191685
Rp1tm2.1Eap/Rp1tm2.1Eap
Tg(Rp1)L2Eap/0
involves: 129S7/SvEvBrd * C57BL/6 		abnormal retina neuronal layer morphology J:191685
abnormal rod electrophysiology J:191685
retina degeneration J:191685
short photoreceptor outer segment J:191685
Rp1tm2.1Eap/Rp1tm2.1Eap
Tg(Rp1)T1Eap/0
involves: 129S7/SvEvBrd * C57BL/6 		abnormal cone electrophysiology J:191685
abnormal rod electrophysiology J:191685
normal vision/eye phenotype J:191685
Rp1tvrm64/Rp1tvrm64
C57BL/6J-Rp1tvrm64/J 		abnormal ocular fundus morphology J:166679
abnormal retina vasculature morphology J:166679
retina photoreceptor degeneration J:166679
short photoreceptor inner segment J:166679
short photoreceptor outer segment J:166679
normal vision/eye phenotype J:166679
Tg(Rp1)L2Eap/0
involves: C57BL/6 		normal vision/eye phenotype J:191685
Tg(Rp1)T1Eap/0
involves: C57BL/6 		normal vision/eye phenotype J:191685
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory