Sox30 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sox30
SRY (sex determining region Y)-box 30
MGI:1341157

18 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sox30^em1Laye/Sox30^em1Laye C57BL/6J-Sox30^em1Laye	abnormal epididymis morphology	J:263980
	abnormal proacrosomal vesicle fusion	J:263980
	abnormal spermatid morphology	J:263980
	abnormal spermatocyte morphology	J:263980
	arrest of spermiogenesis	J:263980
	azoospermia	J:263980
	decreased testis weight	J:263980
	increased male germ cell apoptosis	J:263980
	male infertility	J:263980
	multinucleated giant male germ cells	J:263980
	normal reproductive system phenotype	J:263980
	small testis	J:263980
Sox30^em2Hncs/Sox30^em2Hncs involves: C57BL/6J * DBA * ICR	arrest of spermatogenesis	J:264140
	increased male germ cell apoptosis	J:264140
	male infertility	J:264140
	small epididymis	J:264140
	small testis	J:264140
Sox30^{tm1a(KOMP)Wtsi}/Sox30^{tm1a(KOMP)Wtsi} involves: C57BL/6N	abnormal spermatid morphology	J:255310
	abnormal spermatogenesis	J:255310
	arrest of spermiogenesis	J:255310
	azoospermia	J:255310
	male infertility	J:255310
	multinucleated giant male germ cells	J:255310
	small testis	J:255310
Sox30^{tm1b(KOMP)Wtsi}/Sox30^{tm1b(KOMP)Wtsi} C57BL/6N-Sox30^{tm1b(KOMP)Wtsi}/Bay	abnormal retina inner nuclear layer morphology	J:211773
	increased fasting circulating glucose level	J:211773
	persistence of hyaloid vascular system	J:211773
Sox30^{tm1c(KOMP)Wtsi}/Sox30^{tm1c(KOMP)Wtsi} Tg(Ddx4-cre)1Dcas/0 involves: 129S4/SvJaeSor * C57BL/6N * FVB	arrest of spermiogenesis	J:255310
	azoospermia	J:255310
	male infertility	J:255310
	multinucleated giant male germ cells	J:255310

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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