Tacc3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tacc3
transforming, acidic coiled-coil containing protein 3
MGI:1341163

29 phenotypes from 4 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tacc3^tm1.1Tno/Tacc3^tm1.1Tno involves: C57BL/6	no abnormal phenotype detected	J:126471
Tacc3^tm1.1Tno/Tacc3^tm1.2Tno involves: C57BL/6	no abnormal phenotype detected	J:126471
Tacc3^tm1.1Tno/Tacc3^tm1.2Tno involves: C57BL/6	abnormal mitosis	J:126471
Tacc3^tm1.2Tno/Tacc3^tm1.2Tno involves: C57BL/6	embryonic growth retardation	J:126471
Tacc3^tm1.2Tno/Tacc3^tm1.2Tno involves: C57BL/6	embryonic lethality during organogenesis, complete penetrance	J:126471
Tacc3^tm1Jni/Tacc3^tm1Jni involves: 129P2/OlaHsd * C57BL/6	abnormal definitive hematopoiesis	J:74762
	decreased embryo size	J:74762
	decreased hematopoietic stem cell number	J:74762
	decreased thymocyte number	J:74762
	liver hypoplasia	J:74762
	midline facial cleft	J:74762
	prenatal lethality, complete penetrance	J:74762
	small thymus	J:74762
Tacc3^tm1Tno/Tacc3⁺ involves: C57BL/6	prenatal lethality, incomplete penetrance	J:126471
Tacc3^tm1Tno/Tacc3^tm1.2Tno involves: C57BL/6	embryonic growth retardation	J:126471
Tacc3^tm1Tno/Tacc3^tm1.2Tno involves: C57BL/6	lethality throughout fetal growth and development, complete penetrance	J:126471
Tacc3^tm1Tno/Tacc3^tm1Tno involves: C57BL/6	abnormal axial skeleton morphology	J:126471
	abnormal bone ossification	J:126471
	abnormal cartilage development	J:126471
	abnormal cartilage morphology	J:126471
	abnormal facial morphology	J:126471
	abnormal mitosis	J:126471
	abnormal neurocranium morphology	J:126471
	abnormal sacral vertebrae morphology	J:126471
	abnormal vertebral arch morphology	J:126471
	absent caudal vertebrae	J:126471
	decreased body length	J:126471
	delayed somite formation	J:126471
	embryonic growth retardation	J:126471
	hindlimb paralysis	J:126471
	lumbar vertebral fusion	J:126471
	neonatal lethality, complete penetrance	J:126471
	short tail	J:126471

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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