Scnm1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Scnm1
sodium channel modifier 1
MGI:1341284

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Scn8a^med-J/Scn8a^med-J Scnm1^m1R/Scnm1^m1R involves: C57BL/6 * STOCK Krt71^Ca	normal behavior/neurological phenotype	J:141236
	postnatal lethality	J:141236
Scn8a^med-J/Scn8a^med-J Scnm1^s/Scnm1⁺ involves: C3HeB/FeJ * C57BL/6J	abnormal action potential	J:108906
	abnormal CNS synaptic transmission	J:108906
	abnormal posture	J:108906
	impaired hearing	J:108906
	increased susceptibility to age-related hearing loss	J:108906
	paraparesis	J:108906
	tremors	J:108906
Scn8a^med-J/Scn8a^med-J Scnm1^s/Scnm1^s involves: C57BL/6J	ataxia	J:79617
	dystonia	J:79617
	muscular atrophy	J:79617
	paralysis	J:79617
	premature death	J:79617
Scn8a^med-J/Scn8a^med-J Scnm1^s/Scnm1^s involves: C57BL/6J * STOCK Krt71^Ca	abnormal cell physiology	J:141236
	muscle weakness	J:141236
	premature death	J:141236
Scn8a^med-J/Scn8a^med-J Scnm1^tm1.1Mm/Scnm1^tm1.1Mm involves: C57BL/6 * FVB * SJL * STOCK Krt71^Ca	abnormal cell physiology	J:141236
	hindlimb paralysis	J:141236
	premature death	J:141236
Scnm1^tm1.1Mm/Scnm1^tm1.1Mm Tg(EIIa-cre)C5379Lmgd/0 involves: C57BL/6 * C57BL/6J * FVB * SJL	decreased body weight	J:141236

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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