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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tlr1
toll-like receptor 1
MGI:1341295
6 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tlr1tm1Aki/Tlr1tm1Aki
involves: 129P2/OlaHsd * C57BL/6 		abnormal cytokine secretion J:103395
decreased interleukin-6 secretion J:103395
decreased tumor necrosis factor secretion J:103395
Tlr1tm1Flv/Tlr1tm1Flv
involves: 129S1/Sv 		abnormal macrophage physiology J:95726
decreased immunoglobulin level J:95726
increased susceptibility to bacterial infection J:95726
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory