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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Trpv1
transient receptor potential cation channel, subfamily V, member 1
MGI:1341787
62 phenotypes from 2 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Trpv1tm1Jbd/Trpv1tm1Jbd
involves: 129P2/OlaHsd 		abnormal sensory neuron physiology J:161343
Trpv1tm1Jbd/Trpv1tm1Jbd
involves: 129P2/OlaHsd * C57BL/6J 		abnormal nervous system electrophysiology J:62074
abnormal nociception after inflammation J:62074
abnormal thermal nociception J:62074
Trpv1tm1Jul/Trpv1tm1Jul
B6.129X1-Trpv1tm1Jul 		abnormal behavior J:117778
abnormal chemokine secretion J:154624
abnormal renal tubule morphology J:154624
abnormal urine homeostasis J:154624
normal behavior/neurological phenotype J:117778
decreased anxiety-related response J:117778
glomerulosclerosis J:154624
impaired contextual conditioning behavior J:117778
impaired cued conditioning behavior J:117778
increased interleukin-6 secretion J:154624
increased susceptibility to injury J:154624
increased tumor necrosis factor secretion J:154624
increased urine protein level J:154624
kidney inflammation J:154624
normal nervous system phenotype J:117778
reduced long-term potentiation J:117778
Trpv1tm1Jul/Trpv1tm1Jul
B6.129X1-Trpv1tm1Jul/J 		abnormal action potential J:109767
abnormal hair cycle J:110694
abnormal hair cycle catagen phase J:110694
abnormal hair cycle telogen phase J:110694
abnormal mechanical nociception J:128319
abnormal nervous system electrophysiology J:105254
abnormal neuronal precursor proliferation J:102006
abnormal physiological response to xenobiotic J:96901, J:105525, J:128319, J:132936
abnormal response of heart to induced stress J:116905
abnormal righting response J:153529
abnormal taste sensitivity J:145940
alcohol preference J:153529
normal behavior/neurological phenotype J:132700, J:153529
decreased left ventricle diastolic pressure J:116905
decreased synaptic depression J:132936
impaired ability to fire action potentials J:109767
impaired behavioral response to alcohol J:153529
impaired coordination J:153529
increased alcohol consumption J:153529
increased blood osmolality J:105254
increased body weight J:133914
increased coronary flow rate J:116905
increased left ventricle developed pressure J:116905
increased thermal nociceptive threshold J:96901
reduced long-term depression J:132936
Trpv1tm1Jul/Trpv1tm1Jul
involves: 129X1/SvJ 		abnormal nervous system electrophysiology J:112194
abnormal neuron physiology J:329699
abnormal nociception after inflammation J:61534
abnormal sensory neuron physiology J:61534
decreased abdominal fat pad weight J:137026
decreased fat cell size J:137026
decreased fluid intake J:112194
decreased pruritus J:329699
decreased subcutaneous adipose tissue amount J:137026
decreased susceptibility to diet-induced hepatic steatosis J:137026
decreased susceptibility to diet-induced obesity J:137026
decreased susceptibility to induced hypothermia J:137026
hypoalgesia J:61534, J:197482
impaired ability to fire action potentials J:112194
increased chemical nociceptive threshold J:61534
increased thermal nociceptive threshold J:61534, J:197482
Trpv1tm1Jul/Trpv1tm1Jul
involves: 129X1/SvJ * C57BL/6 		abnormal urination J:78707
decreased susceptibility to endotoxin shock J:104828
normal homeostasis/metabolism phenotype J:104828
impaired febrile response J:104828
increased incidence of tumors by chemical induction J:144978
Gt(ROSA)26Sor/Gt(ROSA)26Sor+
Not Specified 		abnormal body temperature J:132700
abnormal chemical nociception J:132700
abnormal pain threshold J:132700
abnormal physiological response to xenobiotic J:132700
increased thermal nociceptive threshold J:132700
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory