Ndrg1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ndrg1
N-myc downstream regulated gene 1
MGI:1341799

29 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ndrg1^em1Lxli/Ndrg1^em1Lxli C57BL/6N-Ndrg1^em1Lxli	abnormal action potential	J:330126
	abnormal axon morphology	J:330126
	abnormal gait	J:330126
	abnormal motor capabilities/coordination/movement	J:330126
	abnormal sciatic nerve morphology	J:330126
	decreased body weight	J:330126
	decreased myelin sheath thickness	J:330126
	decreased nerve conduction velocity	J:330126
	demyelination	J:330126
	hindlimb paresis	J:330126
	impaired coordination	J:330126
	normal neoplasm	J:330126
	short stride length	J:330126
Ndrg1^str/Ndrg1^str involves: BALB/c * C57BL/6 * NOD/ShiLtWtsi	cataract	J:172770
	decreased body size	J:172770
	decreased nerve conduction velocity	J:172770
	demyelination	J:172770
	hindlimb paralysis	J:172770
	limb grasping	J:172770
	premature death	J:172770
	skeletal muscle atrophy	J:172770
	tremors	J:172770
	weakness	J:172770
Ndrg1^tm1Myta/Ndrg1^tm1Myta involves: 129S1/Sv * 129X1/SvJ * C57BL/6	cataract	J:172770
	decreased body size	J:172770
	decreased nerve conduction velocity	J:172770
	demyelination	J:89888, J:172770
	hindlimb paralysis	J:172770
	limb grasping	J:89888
	paraparesis	J:89888
	peripheral nervous system degeneration	J:89888
	premature death	J:172770
	skeletal muscle atrophy	J:172770
	weakness	J:172770
Ndrg1^{tm2b(KOMP)Wtsi}/Ndrg1^{tm2b(KOMP)Wtsi} C57BL/6N-Ndrg1^{tm2b(KOMP)Wtsi}/Tcp	abnormal gait	J:211773
	decreased bone mineral density	J:211773
	decreased fasting circulating glucose level	J:211773
	decreased grip strength	J:211773
	decreased prepulse inhibition	J:211773
	increased circulating phosphate level	J:211773
	prolonged RR interval	J:211773
	tremors	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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