Gstz1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gstz1
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
MGI:1341859

24 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gstz1^tm1Jmfc/Gstz1^tm1Jmfc 129S4/SvJae-Gstz1^tm1Jmfc	abnormal kidney morphology	J:77040
	abnormal liver morphology	J:77040
	abnormal renal tubule epithelium morphology	J:77040
	hepatic steatosis	J:77040
	increased kidney apoptosis	J:77040
	increased susceptibility to induced morbidity/mortality	J:77040
	ketoaciduria	J:77040, J:86595
	macrovesicular hepatic steatosis	J:77040
	microvesicular hepatic steatosis	J:77040
	oxidative stress	J:77040
	renal necrosis	J:77040
Gstz1^tm1Pgb/Gstz1^tm1Pgb BALB/c-Gstz1^tm1Pgb/AnuApb	abnormal hepatocyte mitochondrial morphology	J:91519
	cellular necrosis	J:91519
	chronic inflammation	J:91519
	decreased body weight	J:91519
	decreased leukocyte cell number	J:91519
	decreased spleen weight	J:91519
	dystrophic cardiac calcinosis	J:91519
	hepatic necrosis	J:91519
	increased kidney weight	J:91519
	increased liver weight	J:91519
	increased susceptibility to induced morbidity/mortality	J:91519
	liver inflammation	J:91519
	macrovesicular hepatic steatosis	J:91519
	premature death	J:91519
	weight loss	J:91519

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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