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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tjp2
tight junction protein 2
MGI:1341872
18 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tjp1tm1.1Whun/Tjp1tm1.1Whun
Tjp2tm2Whun/Tjp2tm2Whun
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * C57BL/6NTac * DBA/2 		abnormal bile canaliculus morphology J:306936
abnormal hepatic cord morphology J:306936
abnormal hepatic duct morphology J:306936
abnormal hepatocyte morphology J:306936
abnormal liver morphology J:306936
abnormal liver physiology J:306936
abnormal liver sinusoid morphology J:306936
increased bile salt level J:306936
increased circulating alanine transaminase level J:306936
increased circulating alkaline phosphatase level J:306936
increased circulating aspartate transaminase level J:306936
increased circulating bilirubin level J:306936
increased circulating LDL cholesterol level J:306936
increased hepatocyte proliferation J:306936
increased liver weight J:306936
postnatal lethality, incomplete penetrance J:306936
premature death J:306936
small liver J:306936
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory