Ehd1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ehd1
EH-domain containing 1
MGI:1341878

31 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ehd1^tm1.1Haba/Ehd1^tm1.1Haba involves: 129P2/OlaHsd * C57BL/6 * SJL	no abnormal phenotype detected	J:160452
Ehd1^tm1.2Haba/Ehd1^tm1.2Haba FVB.Cg-Ehd1^tm1.2Haba	decreased testis weight	J:160452
	male infertility	J:160452
	postnatal lethality, incomplete penetrance	J:160452
Ehd1^tm1.2Haba/Ehd1^tm1.2Haba involves: 129P2/OlaHsd * C57BL/6J * FVB/N	abnormal acrosome morphology	J:160452
	abnormal eyelid aperture	J:160452
	abnormal germ cell morphology	J:160452
	abnormal male meiosis	J:160452
	abnormal Sertoli cell phagocytosis	J:160452
	abnormal spermatid morphology	J:160452
	abnormal spermatocyte morphology	J:160452
	abnormal spermatogenesis	J:160452
	abnormal spermatogonia morphology	J:160452
	abnormal spermiation	J:160452
	anophthalmia	J:160452
	arrest of spermiogenesis	J:160452
	azoospermia	J:160452
	decreased body size	J:160452
	decreased body weight	J:160452
	decreased testis weight	J:160452
	developmental cataract	J:160452
	increased male germ cell apoptosis	J:160452
	male infertility	J:160452
	malocclusion	J:160452
	microphthalmia	J:160452
	perinatal lethality, incomplete penetrance	J:160452
	postnatal lethality, incomplete penetrance	J:160452
	seminiferous tubule degeneration	J:160452
Ehd1^{tm1a(EUCOMM)Wtsi}/Ehd1⁺ C57BL/6N-Ehd1^{tm1a(EUCOMM)Wtsi}/Wtsi	increased circulating chloride level	J:175295
	increased mean corpuscular hemoglobin	J:175295
Ehd1^{tm1a(EUCOMM)Wtsi}/Ehd1^{tm1a(EUCOMM)Wtsi} C57BL/6N-Ehd1^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal eyelid aperture	J:175295
Ehd1^tm1Mhor/Ehd1^tm1Mhor either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * Swiss Webster)	abnormal cell physiology	J:121819
	normal cellular phenotype	J:121819
Ehd1^tm1Mhor/Ehd1^tm1Mhor involves: 129S6/SvEvTac	abnormal cell migration	J:120764
Ehd1^tm1Mhor/Ehd1^tm1Mhor involves: 129S6/SvEvTac	decreased fibroblast cell migration	J:120764

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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