Hey2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hey2
hairy/enhancer-of-split related with YRPW motif 2
MGI:1341884

35 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Hey1^tm1Gess/Hey1⁺ Hey2^tm1Gess/Hey2^tm1Gess involves: 129 * C57BL/6	premature death	J:89444
Hey1^tm1Gess/Hey1^tm1Gess Hey2^tm1Gess/Hey2⁺ involves: 129 * C57BL/6	prenatal lethality, incomplete penetrance	J:89444
Hey1^tm1Gess/Hey1^tm1Gess Hey2^tm1Gess/Hey2^tm1Gess involves: 129 * C57BL/6	abnormal artery morphology	J:89444
	abnormal cardinal vein morphology	J:89444
	abnormal dorsal aorta morphology	J:89444
	abnormal heart ventricle morphology	J:89444
	abnormal intersomitic vessel morphology	J:89444
	abnormal neural tube morphology	J:89444
	abnormal placenta labyrinth morphology	J:89444
	abnormal placental labyrinth vasculature morphology	J:89444
	abnormal umbilical cord morphology	J:89444
	abnormal vitelline vascular remodeling	J:89444
	absent myocardial trabeculae	J:89444
	decreased angiogenesis	J:89444
	distended pericardium	J:89444
	embryonic growth retardation	J:89444
	hemorrhage	J:89444
	incomplete somite formation	J:89444
	pale yolk sac	J:89444
	prenatal lethality, complete penetrance	J:89444
	thin myocardium	J:89444
Hey1^tm1Kkb/Hey1^tm1Kkb Hey2^tm1Kkb/Hey2^tm1Kkb involves: 129S7/SvEvBrd * C57BL/6	abnormal artery development	J:96337
	abnormal artery morphology	J:96337
	abnormal atrioventricular cushion morphology	J:96337
	abnormal cardiac epithelial to mesenchymal transition	J:96337
	abnormal dorsal aorta morphology	J:96337
	abnormal heart development	J:96337
	abnormal myocardial fiber morphology	J:96337
	abnormal telencephalon morphology	J:96337
	abnormal vitelline vascular remodeling	J:96337
	common atrium	J:96337
	common ventricle	J:96337
	embryonic lethality during organogenesis, complete penetrance	J:96337
	hemorrhage	J:96337
	small first pharyngeal arch	J:96337
	small second pharyngeal arch	J:96337
	thin ventricular wall	J:96337
	trabecula carnea hypoplasia	J:96337
Hey2^tm2Eno/Hey2^tm2Eno Rr76^em1Ona/Rr76^em1Ona involves: 129/SvEv * C57BL/6 * DBA	normal cardiovascular system phenotype	J:288309

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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