B4galnt1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

B4galnt1
beta-1,4-N-acetyl-galactosaminyl transferase 1
MGI:1342057

36 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
B4galnt1^tm1Rlp/B4galnt1⁺ Hexb^tm1Rlp/Hexb^tm1Rlp involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6	impaired coordination	J:53080
	impaired righting response	J:53080
B4galnt1^tm1Rlp/B4galnt1^tm1Rlp Hexb^tm1Rlp/Hexb^tm1Rlp involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6	abnormal macrophage morphology	J:53080
	abnormal neuron morphology	J:53080
	abnormal Purkinje cell morphology	J:53080
	abnormal renal tubule epithelium morphology	J:53080
	ataxia	J:53080
	impaired coordination	J:53080
	normal mortality/aging	J:53080
	Purkinje cell degeneration	J:53080
	seminiferous tubule degeneration	J:53080
B4galnt1^tm1Rlp/B4galnt1^tm1Rlp St3gal5^tm1Rlp/St3gal5^tm1Rlp involves: 129S6/SvEvTac * C57BL/6	abnormal axon morphology	J:96830
	abnormal brainstem morphology	J:96830
	abnormal cerebellum white matter morphology	J:96830
	abnormal ganglioside level	J:96830
	abnormal lipid homeostasis	J:96830
	abnormal oligodendrocyte morphology	J:96830
	abnormal paranodal axoglial junction morphology	J:96830
	abnormal paranode morphology	J:96830
	abnormal spinal cord white matter morphology	J:96830
	astrocytosis	J:96830
	ataxia	J:96830
	axon degeneration	J:96830
	axonal spheroids	J:96830
	brain vacuoles	J:96830
	decreased brain size	J:96830
	increased brain apoptosis	J:96830
	neurodegeneration	J:96830
	paraparesis	J:96830
	premature death	J:96830
	tremors	J:96830
B4galnt1^tm1Rlp/B4galnt1^tm1Rlp St8sia1^tm1Rlp/St8sia1^tm1Rlp involves: 129S6/SvEvTac	abnormal breathing pattern	J:67955
	abnormal spermatogenesis	J:67955
	audiogenic seizures	J:67955
	male infertility	J:67955
	normal nervous system phenotype	J:67955
	premature death	J:67955
	seizures	J:67955
	tonic-clonic seizures	J:67955

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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