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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ikzf1
IKAROS family zinc finger 1
MGI:1342540
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ikzf1tm1(Pax5)Mbu/Ikzf1+
Tg(Lck-cre)1Cwi/0
involves: 129P2/OlaHsd * C57BL/6 		increased T cell derived lymphoma incidence J:118111
Ikzf1tm1(Pax5)Mbu/Ikzf1tm1(Pax5)Mbu
involves: 129P2/OlaHsd * C57BL/6 		abnormal B cell number J:80815
abnormal dendritic cell morphology J:80815
abnormal T cell differentiation J:80815
Ikzf1tm1(Pax5)Mbu/Ikzf1tm1(Pax5)Mbu
Tg(Mx1-cre)1Cgn/0
involves: 129P2/OlaHsd * C57BL/6 * CBA 		abnormal T cell differentiation J:80815
arrested T cell differentiation J:80815
increased B cell number J:80815
increased early pro-B cell number J:80815
thymus hypoplasia J:80815
Ikzf1tm1.1(Pax5)Mbu/Ikzf1+
involves: 129P2/OlaHsd * C57BL/6 		abnormal B cell differentiation J:80815
abnormal erythropoiesis J:80815
decreased double-positive T cell number J:118111
enlarged lymph nodes J:118111
enlarged spleen J:118111
enlarged thymus J:118111
increased B cell number J:80815
increased lymphoma incidence J:118111
increased pro-B cell number J:80815
increased T cell derived lymphoma incidence J:118111
premature death J:118111
thymus hypoplasia J:118111
Ikzf1tm1.1(Pax5)Mbu/Ikzf1+
Tcf3tm1Mbu/Tcf3tm1Mbu
Commd10Tg(Vav1-icre)A2Kio/Commd10+
involves: 129P2/OlaHsd * C57BL/10 * CBA/Ca 		abnormal immunoglobulin heavy chain V(D)J recombination J:137719
normal immune system phenotype J:137719
Ikzf1tm1Kast/Ikzf1+
Tg(BCR/ABL)623Hkp/0
involves: 129S2/SvPas * C57BL/6 * CBA 		increased acute lymphoblastic leukemia incidence J:160846
Ikzf1tm3.1Mbu/Ikzf1tm3.1Mbu
Cd79atm1(cre)Reth/Cd79a+
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv * BALB/c * C57BL/6 * SJL 		decreased pro-B cell number J:209928
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory