Kat2a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kat2a
K(lysine) acetyltransferase 2A
MGI:1343101

52 phenotypes from 6 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kat2a^tm1Nkt/Kat2a^tm1Nkt involves: 129X1/SvJ * CD-1	abnormal neural tube closure	J:65264
	abnormal vitelline vasculature morphology	J:65264
	decreased embryo size	J:65264
	embryonic growth arrest	J:65264
	embryonic lethality during organogenesis, complete penetrance	J:65264
	hemorrhage	J:65264
Kat2a^tm1Roth/Kat2a⁺ involves: 129/Sv * 129S7/SvEvBrd	decreased lumbar vertebrae number	J:137385
Kat2a^tm1Roth/Kat2a^tm1Roth involves: 129S7/SvEvBrd * C57BL/6J	abnormal chordamesoderm morphology	J:65002
	abnormal extraembryonic coelom morphology	J:65002
	abnormal head mesenchyme morphology	J:65002
	abnormal mesoderm development	J:65002
	abnormal neural tube morphology	J:65002
	abnormal paraxial mesoderm morphology	J:65002
	absent notochord	J:65002
	absent somites	J:65002
	embryonic growth retardation	J:65002
	embryonic lethality, complete penetrance	J:65002
Kat2a^tm1Roth/Kat2a^tm3.2Roth involves: 129/Sv * 129S7/SvEvBrd	no abnormal phenotype detected	J:132940
Kat2a^tm1Roth/Kat2a^tm3Roth 129-Kat2a^tm1Roth/Kat2a^tm3Roth	exencephaly	J:132940
Kat2a^tm1Roth/Kat2a^tm3Roth involves: 129 * 129S7/SvEvBrd	abnormal sternebra number	J:137385
	increased rib number	J:137385
	lumbar vertebral transformation	J:137385
	rib fusion	J:137385
	small xiphoid process	J:137385
	thoracic vertebral transformation	J:137385
Kat2a^tm1Roth/Kat2a^tm3Roth involves: 129 * 129S7/SvEvBrd * C57BL/6	abnormal breathing pattern	J:132940
	abnormal neural tube closure	J:132940
	blepharoptosis	J:132940
	decreased body size	J:132940
	decreased embryo size	J:132940
	decreased fetal size	J:132940
	exencephaly	J:132940
	hunched posture	J:132940
	normal nervous system phenotype	J:132940
	open neural tube	J:132940
	postnatal lethality, incomplete penetrance	J:132940
	normal respiratory system phenotype	J:132940
Kat2a^tm2Roth/Kat2a^tm2Roth involves: 129S7/SvEvBrd * C57BL/6J	abnormal metencephalon morphology	J:121357
	abnormal midbrain morphology	J:121357
	abnormal telencephalon development	J:121357
	decreased embryo size	J:121357
	decreased fibroblast proliferation	J:121357
	normal embryo phenotype	J:121357
	embryonic lethality during organogenesis, incomplete penetrance	J:121357
	exencephaly	J:121357
	failure of somite differentiation	J:121357
	incomplete rostral neuropore closure	J:121357
	increased embryonic tissue cell apoptosis	J:121357
	open neural tube	J:121357
Kat2a^tm3.1Roth/Kat2a^tm3.1Roth involves: 129	abnormal embryo development	J:132940
	abnormal embryonic growth/weight/body size	J:132940
	embryonic lethality during organogenesis, complete penetrance	J:132940
Kat2a^tm3.1Roth/Kat2a^tm3.2Roth Tg(Pcp2-cre)2Mpin/0 involves: 129	abnormal cerebellum vermis morphology	J:179021
	abnormal gait	J:179021
	normal behavior/neurological phenotype	J:179021
Kat2a^tm3.2Roth/Kat2a^tm3.2Roth involves: 129	no abnormal phenotype detected	J:132940
Kat2a^tm3.2Roth/Kat2a^tm3.2Roth involves: 129	normal skeleton phenotype	J:137385
Kat2a^tm3Roth/Kat2a⁺ involves: 129	decreased lumbar vertebrae number	J:137385
Kat2a^tm3Roth/Kat2a^tm3.1Roth involves: 129	abnormal breathing pattern	J:132940
Kat2a^tm3Roth/Kat2a^tm3.1Roth involves: 129	exencephaly	J:132940
Kat2a^tm3Roth/Kat2a^tm3Roth involves: 129	abnormal sternebra number	J:137385
	increased rib number	J:137385
	lumbar vertebral transformation	J:137385
	rib fusion	J:137385
	small xiphoid process	J:137385
	thoracic vertebral transformation	J:137385
	vertebral transformation	J:137385
Kat2a^tm3Roth/Kat2a^tm3Roth involves: 129 * C57BL/6	abnormal breathing pattern	J:132940
	decreased body size	J:132940
	decreased body weight	J:132940
	decreased embryo size	J:132940
	exencephaly	J:132940
	open neural tube	J:132940
	postnatal lethality, complete penetrance	J:132940

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