Robo3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Robo3
roundabout guidance receptor 3
MGI:1343102

26 phenotypes from 4 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dbx1^tm2(cre)Apie/Dbx1⁺ Robo3^tm1.1Ache/Robo3^tm1.1Ache involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	abnormal medulla oblongata morphology	J:165285
	abnormal pre-Botzinger complex morphology	J:165285
	abnormal pre-Botzinger complex physiology	J:165285
	neonatal lethality, complete penetrance	J:165285
Egr2^tm2(cre)Pch/Egr2⁺ Robo3^tm1.1Ache/Robo3^tm1.1Ache involves: 129S2/SvPas	abnormal auditory brainstem response	J:158918
	abnormal brain commissure morphology	J:158918
	abnormal horizontal vestibuloocular reflex	J:158918
	abnormal innervation	J:158918
	abnormal optokinetic reflex	J:158918
	abnormal reflex	J:158918
Egr2^tm2(cre)Pch/Egr2⁺ Robo3^tm1.1Ache/Robo3^tm1.1Ache Tg(Mnx1-EGFP)#Tmj/0 involves: 129S2/SvPas * C57BL/6 * DBA	abnormal pons morphology	J:158918
Ptf1a^{tm1.1(cre)Cvw}/Ptf1a⁺ Robo3^tm1.1Ache/Robo3^tm1.1Ache involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ	abnormal brain commissure morphology	J:158918
	abnormal innervation	J:158918
	abnormal motor coordination/balance	J:158918
	ataxia	J:158918
	impaired coordination	J:158918
Robo3^em1(IMPC)H/Robo3⁺ C57BL/6NTac-Robo3^em1(IMPC)H/H	abnormal retina morphology	J:211773
	increased circulating bilirubin level	J:211773
	increased heart weight	J:211773
Robo3^em1(IMPC)H/Robo3^em1(IMPC)H C57BL/6NTac-Robo3^em1(IMPC)H/H	preweaning lethality, complete penetrance	J:211773
Robo3^m1J/Robo3^m1J C57BL/6J-Robo3^m1J/GrsrJ	ataxia	J:178742
	impaired balance	J:178742
	normal mortality/aging	J:178742
Robo3^tm1Matl/Robo3⁺ Tg(Atoh1-lacZ)1Jejo/? Not Specified	abnormal dorsal interneuron 1 morphology	J:142117
Robo3^tm1Matl/Robo3^tm1Matl either: (involves: 129/Sv * C57BL/6) or (involves: 129/Sv * CD-1)	abnormal axon guidance	J:89438
	abnormal floor plate morphology	J:89438
	perinatal lethality, complete penetrance	J:89438
Robo3^tm1Matl/Robo3^tm1Matl involves: C57BL/6	abnormal breathing pattern	J:165285
	abnormal pre-Botzinger complex physiology	J:165285
	cyanosis	J:165285
	neonatal lethality, complete penetrance	J:165285
Robo3^tm1Matl/Robo3^tm1Matl Not Specified	abnormal brain commissure morphology	J:158918
Robo3^tm1Matl/Robo3^tm1Matl Tg(Mnx1-EGFP)#Tmj/0 involves: C57BL/6 * DBA	abnormal pons morphology	J:158918

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