Ikzf4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ikzf4
IKAROS family zinc finger 4
MGI:1343139

23 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Foxp3^{tm4(YFP/icre)Ayr}/Foxp3^{tm4(YFP/icre)Ayr} Ikzf4^tm1Djr/Ikzf4^tm1Djr involves: 129S1/Sv * 129X1/SvJ	abnormal small intestine morphology	J:294549
	chronic inflammation	J:294549
	decreased regulatory T cell number	J:294549
	decreased small intestinal microvillus size	J:294549
	enlarged lymph nodes	J:294549
	enlarged spleen	J:294549
	glomerulonephritis	J:294549
	granulomatous inflammation	J:294549
	increased germinal center B cell number	J:294549
	increased immunoglobulin level	J:294549
	increased spleen B cell follicle number	J:294549
	increased spleen germinal center number	J:294549
	increased susceptibility to experimental autoimmune encephalomyelitis	J:294549
	increased T cell number	J:294549
	increased T follicular helper cell number	J:294549
	small intestinal inflammation	J:294549
Ikzf4^{em1(IMPC)Rbrc}/Ikzf4^{em1(IMPC)Rbrc} C57BL/6NJcl-Ikzf4^{em1(IMPC)Rbrc}/Rbrc	abnormal behavior	J:211773
	abnormal kidney morphology	J:211773
	decreased locomotor activity	J:211773
	decreased thigmotaxis	J:211773
Ikzf4^tm1.1Etms/Ikzf4^tm1.1Etms Not Specified	chronic inflammation	J:294549
	decreased T cell proliferation	J:295208
	normal hematopoietic system phenotype	J:295208
	normal immune system phenotype	J:295208
	increased susceptibility to experimental autoimmune encephalomyelitis	J:295208
Ikzf4^tm1Djr/Ikzf4^tm1Djr Tg(Cd4-cre)1Cwi/0 involves: C57BL/6 * DBA/2	chronic inflammation	J:294549

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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