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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Klk8
kallikrein related-peptidase 8
MGI:1343327
16 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Klk8em1(IMPC)Ccpcz/Klk8em1(IMPC)Ccpcz
C57BL/6N-Klk8em1(IMPC)Ccpcz/Ccpcz 		abnormal kidney morphology J:211773
abnormal spleen morphology J:211773
decreased lymphocyte cell number J:211773
enlarged spleen J:211773
Klk8tm1Lth/Klk8tm1Lth
involves: 129P2/OlaHsd * C57BL/6 		abnormal excitatory postsynaptic potential J:71533
normal behavior/neurological phenotype J:71533
increased susceptibility to pharmacologically induced seizures J:71533
increased susceptibility to xenobiotic induced morbidity/mortality J:71533
normal nervous system phenotype J:71533
Klk8tm1Shio/Klk8tm1Shio
involves: 129P2/OlaHsd * C57BL/6J 		abnormal brain interneuron morphology J:68653
abnormal GABAergic neuron morphology J:68653
abnormal hippocampus morphology J:68653
abnormal hippocampus pyramidal cell layer J:68653
abnormal hippocampus pyramidal cell morphology J:68653
abnormal synaptic bouton morphology J:68653
decreased CNS synapse formation J:68653
normal nervous system phenotype J:68653
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory