Bub3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bub3
BUB3 mitotic checkpoint protein
MGI:1343463

8 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Bub3^tm1Jvd/Bub3⁺ Not Specified	abnormal cell cycle checkpoint function	J:81546, J:105717
	abnormal mitosis	J:81546, J:105717
	aneuploidy	J:81546, J:105717
	increased incidence of tumors by chemical induction	J:81546
Bub3^tm1Jvd/Bub3^tm1Jvd Not Specified	embryonic lethality between implantation and somite formation, complete penetrance	J:81546
Bub3^tm1Khac/Bub3^tm1Khac either: (involves: 129P2/OlaHsd) or (involves: 129S1/Sv)	abnormal cell nucleus morphology	J:64874
	abnormal chromosome morphology	J:64874
	embryonic lethality between implantation and somite formation, complete penetrance	J:64874
	inner cell mass degeneration	J:64874

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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