Rorb Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rorb
RAR-related orphan receptor beta
MGI:1343464

48 phenotypes from 11 alleles in 12 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rorb^hstp-2J/Rorb^hstp-2J B6.Cg-Rorb^hstp-2J/GrsrJ	abnormal gait	J:337403
	abnormal photoreceptor inner segment morphology	J:337403
	abnormal photoreceptor outer segment morphology	J:337403
	abnormal retina cone cell inner segment morphology	J:337403
	abnormal retina cone cell outer segment morphology	J:337403
	disorganized photoreceptor inner segment	J:337403
	disorganized photoreceptor outer segment	J:337403
	disorganized retina layers	J:337403
Rorb^hstp-3J/Rorb^hstp-3J B6.Cg-Tyr^c-2J Rorb^hstp-3J/GrsrJ	abnormal gait	J:337403
Rorb^hstp-3J/Rorb^hstp-3J B6.Cg-Tyr^c-2J Rorb^hstp-3J/GrsrJ	normal vision/eye phenotype	J:337403
Rorb^hstp-4J/Rorb^hstp-4J B6.Cg-Tyr^c-2J Rorb^hstp-4J/GrsrJ	abnormal gait	J:337403
Rorb^hstp-4J/Rorb^hstp-4J B6.Cg-Tyr^c-2J Rorb^hstp-4J/GrsrJ	normal vision/eye phenotype	J:337403
Rorb^hstp/Rorb^hstp C57BL/6J-Rorb^hstp/J	abnormal eye electrophysiology	J:148753
	abnormal gait	J:148753
	abnormal neuron morphology	J:337403
	abnormal retina ganglion layer morphology	J:148753
	normal behavior/neurological phenotype	J:337403
	normal hearing/vestibular/ear phenotype	J:148753
	increased susceptibility to age-related retinal degeneration	J:148753
	limb grasping	J:148753
	retina photoreceptor degeneration	J:148753
	normal vision/eye phenotype	J:337403
Rorb^m1Btlr/Rorb^m1Btlr C57BL/6J-Rorb^m1Btlr	abnormal gait	J:145609
	limb grasping	J:145609
	male infertility	J:145609
Rorb^m2Btlr/Rorb^m2Btlr C57BL/6J-Rorb^m2Btlr	impaired limb coordination	J:221488
Rorb^m3Btlr/Rorb^m3Btlr C57BL/6J-Rorb^m3Btlr	abnormal gait	J:255292
Rorb^m3Btlr/Rorb^m3Btlr C57BL/6J-Rorb^m3Btlr	impaired limb coordination	J:255292
Rorb^{tm1.1(cre)Hze}/Rorb⁺ involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCr	no abnormal phenotype detected	J:146821
Rorb^{tm1.1(cre)Hze}/Rorb^hstp involves: 129S6/SvEvTac * C57BL/6J	abnormal gait	J:337403
Rorb^tm1.1Df/Rorb^tm1.1Df involves: 129S1/Sv * C57BL/6J	abnormal cone electrophysiology	J:242481
	abnormal gait	J:205743
	abnormal retina development	J:205743
	abnormal retina ganglion cell morphology	J:205743
	abnormal retina inner plexiform layer morphology	J:205743
	abnormal rod electrophysiology	J:242481
	absent amacrine cells	J:205743
	absent retina horizontal cells	J:205743
	decreased retina rod cell number	J:242481
	disorganized retina outer plexiform layer	J:205743
	increased retina cone cell number	J:242481
	increased retina ganglion cell number	J:205743
	thin retina inner nuclear layer	J:205743
	normal vision/eye phenotype	J:242481
Rorb^tm1Mba/Rorb^tm1Mba involves: 129P2/OlaHsd	abnormal cone electrophysiology	J:242481
	abnormal retina inner plexiform layer morphology	J:242481
	abnormal rod electrophysiology	J:242481
	absent amacrine cells	J:242481
	absent photoreceptor inner segment	J:242481
	absent photoreceptor outer segment	J:242481
	absent retina horizontal cells	J:242481
	absent retina rod cells	J:242481
	disorganized retina outer plexiform layer	J:242481
	increased retina cone cell number	J:242481
Rorb^tm1Mba/Rorb^tm1Mba involves: 129P2/OlaHsd * C57BL/6	abnormal eye physiology	J:48923
	abnormal gait	J:48923
	abnormal learning/memory/conditioning	J:48923
	abnormal motor capabilities/coordination/movement	J:48923
	abnormal retina morphology	J:48923
	abnormal sexual interaction	J:48923
	abnormal social/conspecific interaction behavior	J:48923
	normal behavior/neurological phenotype	J:48923
	decreased aggression	J:48923
	decreased body size	J:48923
	decreased exploration in new environment	J:48923
	disorganized retina layers	J:48923
	impaired coordination	J:48923
	limb grasping	J:48923
	normal nervous system phenotype	J:48923
	retina degeneration	J:48923
Rorb^tm2.1Df/Rorb^tm2.1Df involves: 129S1/Sv * C57BL/6J	abnormal retina cone cell morphology	J:242481
	decreased retina rod cell number	J:242481
	increased retina cone cell number	J:242481
	normal vision/eye phenotype	J:242481

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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