Msh6 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Msh6
mutS homolog 6
MGI:1343961

11 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Msh6^m1Btlr/Msh6^m1Btlr C57BL/6J-Msh6^m1Btlr	decreased IgE level	J:255208
Msh6^tm1Htr/Msh6^tm1Htr involves: 129P2/OlaHsd * FVB/N	decreased tumor-free survival time	J:59561
	increased gastrointestinal tumor incidence	J:59561
	increased hemolymphoid system tumor incidence	J:59561
	increased lymphoma incidence	J:59561
	increased skin tumor incidence	J:59561
	increased uterus tumor incidence	J:59561
Msh6^tm1Rak/Msh6^tm1Rak involves: 129/Sv * C57BL/6J * SJL	increased gastrointestinal tumor incidence	J:44428
	increased lymphoma incidence	J:44428
	increased tumor incidence	J:44428
	premature death	J:44428
Msh6^tm1Wed/Msh6⁺ involves: 129/Sv * C57BL/6J * SJL	increased lymphoma incidence	J:92555
Msh6^tm1Wed/Msh6^tm1Wed involves: 129/Sv * C57BL/6J * SJL	decreased tumor-free survival time	J:92555
	increased basal cell carcinoma incidence	J:92555
	increased intestinal adenoma incidence	J:92555
	increased lymphoma incidence	J:92555
	increased tumor incidence	J:92555

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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