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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rpgr
retinitis pigmentosa GTPase regulator
MGI:1344037
27 phenotypes from 7 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
RpgrRd9/Rpgr+
C57BL/6-RpgrRd9 		abnormal retina morphology J:75095, J:237833
RpgrRd9/Y
C57BL/6-RpgrRd9 		abnormal cone electrophysiology J:237833
abnormal ocular fundus morphology J:75095, J:237833
abnormal retina cone cell morphology J:237833
abnormal retina photoreceptor layer morphology J:237833
abnormal retina pigmentation J:237833
abnormal retina rod cell outer segment morphology J:237833
abnormal retina vasculature morphology J:237833
decreased a-wave amplitude J:237833
decreased b-wave amplitude J:237833
retina degeneration J:237833
retina outer nuclear layer degeneration J:75095, J:237833
telangiectasia J:237833
thin retina outer nuclear layer J:237833
RpgrRd9/RpgrRd9
C57BL/6-RpgrRd9 		abnormal ocular fundus morphology J:75095, J:237833
abnormal retina pigmentation J:237833
abnormal retina vasculature morphology J:237833
decreased a-wave amplitude J:237833
decreased b-wave amplitude J:237833
telangiectasia J:237833
Rpgrtm1.1Sgj/Y
involves: 129 * BALB/c 		abnormal cone electrophysiology J:213970
abnormal rod electrophysiology J:213970
retina degeneration J:213970
thin retina outer nuclear layer J:213970
Rpgrtm1.1Sgj/Rpgrtm1.1Sgj
involves: 129 * BALB/c 		abnormal cone electrophysiology J:213970
abnormal rod electrophysiology J:213970
retina degeneration J:213970
thin retina outer nuclear layer J:213970
Rpgrtm1Tili/Rpgrtm1Tili
involves: 129S4/SvJae 		abnormal ocular fundus morphology J:232177
abnormal retina cone cell morphology J:232177
Rpgrtm1Tili/Rpgrtm1Tili
involves: 129S4/SvJae * C57BL/6 		abnormal eye physiology J:61371
abnormal retina cone cell morphology J:61371
abnormal retina morphology J:61371
abnormal retina rod cell outer segment morphology J:61371
retina cone cell degeneration J:82755
retina degeneration J:61371
retina photoreceptor degeneration J:61371
retina rod cell degeneration J:82755
short photoreceptor outer segment J:61371
thin retina outer nuclear layer J:61371
Rpgrtm1Tili/Rpgrtm1Tili
Tg(CMV-Rpgr)1Tili/0
involves: 129S4/SvJae * C57BL/6 		abnormal eye physiology J:87299
abnormal retina morphology J:87299
retina degeneration J:87299
Rpgrtm1Wbrg/Rpgrtm1Wbrg
B6.129P2-Rpgrtm1Wbrg 		abnormal cone electrophysiology J:160802
abnormal photoreceptor inner segment morphology J:160802
abnormal photoreceptor outer segment morphology J:160802
abnormal rod electrophysiology J:160802
thin retina outer nuclear layer J:160802
Rpgrtm1Wbrg/Rpgrtm1Wbrg
C.129P2-Rpgrtm1Wbrg 		abnormal cone electrophysiology J:160802
abnormal rod electrophysiology J:160802
decreased retina cone cell number J:160802
normal vision/eye phenotype J:160802
Tg(CAG-Rpgr)mRDefWrght/0
C57BL/6-Tg(CAG-Rpgr)mRDefWrght 		retina photoreceptor degeneration J:181417
Tg(CAG-Rpgr)mRDefWrght/0
Rpgrtm1Tili/Rpgrtm1Tili
involves: 129S4/SvJae * C57BL/6J 		abnormal retina cone cell morphology J:181417
abnormal retina outer nuclear layer morphology J:181417
disorganized photoreceptor outer segment J:181417
retina photoreceptor degeneration J:181417
short photoreceptor inner segment J:181417
short photoreceptor outer segment J:181417
Tg(CAG-Rpgr)mROrfWrght/0
Rpgrtm1Tili/Rpgrtm1Tili
involves: 129S4/SvJae * C57BL/6J 		normal vision/eye phenotype J:181417
Tg(CMV-Rpgr)1Tili/0
involves: C57BL/6 		abnormal eye physiology J:87299
abnormal retina morphology J:87299
retina degeneration J:87299
Tg(CMV-Rpgr)1Tili/Tg(CMV-Rpgr)1Tili
involves: C57BL/6 		abnormal retina morphology J:87299
retina degeneration J:87299
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory