Arih2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arih2
ariadne RBR E3 ubiquitin protein ligase 2
MGI:1344361

23 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arih2^{tm1.1(KOMP)Vlcg}/Arih2⁺ C57BL/6N-Arih2^{tm1.1(KOMP)Vlcg}/Ucd	abnormal embryo size	J:211773
	abnormal heart morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal urinary bladder morphology	J:211773
	cystolithiasis	J:211773
	embryonic growth retardation	J:211773
	enlarged heart	J:211773
	polycystic kidney	J:211773
Arih2^{tm1.1(KOMP)Vlcg}/Arih2^{tm1.1(KOMP)Vlcg} C57BL/6N-Arih2^{tm1.1(KOMP)Vlcg}/Ucd	abnormal embryo size	J:211773
	embryonic growth retardation	J:211773
	preweaning lethality, complete penetrance	J:211773
Arih2^tm1Mak/Arih2^tm1Mak B6.129P2-Arih2^tm1Mak	abnormal dendritic cell physiology	J:191066
	abnormal liver physiology	J:191066
	increased apoptosis	J:191066
	increased inflammatory response	J:191066
	lethality throughout fetal growth and development, complete penetrance	J:191066
	liver hypoplasia	J:191066
Arih2^tm1Mak/Arih2^tm1Mak involves: 129P2/OlaHsd * C57BL/6	cachexia	J:191066
	decreased body size	J:191066
	dermatitis	J:191066
	heart inflammation	J:191066
	increased inflammatory response	J:191066
	liver inflammation	J:191066
	lung inflammation	J:191066
	postnatal lethality, incomplete penetrance	J:191066

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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