Arih1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arih1
ariadne RBR E3 ubiquitin protein ligase 1
MGI:1344363

17 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arih1^em1(IMPC)Tcp/Arih1⁺ C57BL/6N-Arih1^em1(IMPC)Tcp/Tcp	abnormal skin morphology	J:211773
	abnormal sternum morphology	J:211773
	decreased anxiety-related response	J:211773
	decreased prepulse inhibition	J:211773
	enlarged urinary bladder	J:211773
	hyperactivity	J:211773
	increased exploration in new environment	J:211773
	short tibia	J:211773
Arih1^em1(IMPC)Tcp/Arih1^em1(IMPC)Tcp C57BL/6N-Arih1^em1(IMPC)Tcp/Tcp	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Arih1^em3Gpt/Arih1^em3Gpt Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj}/Gt(ROSA)26Sor⁺ involves: 129S4/SvJae * C57BL/6JGpt	decreased interferon-beta secretion	J:330879
	decreased interleukin-6 secretion	J:330879
	increased susceptibility to Herpesvirales infection	J:330879
	increased susceptibility to Herpesvirales infection induced morbidity/mortality	J:330879
Arih1^em3Gpt/Arih1^em3Gpt Lyz2^em1(icre)Gpt/Lyz2⁺ C57BL/6JGpt-Arih1^em3Gpt Lyz2^em1(icre)Gpt	decreased circulating interferon-beta level	J:330879
	decreased circulating interleukin-6 level	J:330879
	decreased interferon-beta secretion	J:330879
	decreased interleukin-6 secretion	J:330879
	normal immune system phenotype	J:330879
	increased susceptibility to Herpesvirales infection	J:330879
	increased susceptibility to Herpesvirales infection induced morbidity/mortality	J:330879

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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