Prkra Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkra
protein kinase, interferon inducible double stranded RNA dependent activator
MGI:1344375

33 phenotypes from 7 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prkra^em1(IMPC)H/Prkra^em1(IMPC)H C57BL/6N-Prkra^em1(IMPC)H/H	abnormal ear morphology	J:211773
	decreased circulating alkaline phosphatase level	J:211773
	decreased prepulse inhibition	J:211773
	increased blood urea nitrogen level	J:211773
	increased circulating cholesterol level	J:211773
	increased freezing behavior	J:211773
	increased grip strength	J:211773
	male infertility	J:211773
Prkra^lear-2J/Prkra^lear-2J involves: C57BL/6J	decreased body size	J:223062
	impaired hearing	J:223062
	reduced fertility	J:223062
	small ears	J:223062
Prkra^lear-3J/Prkra^lear-3J B6.Cg-Prkra^lear-3J/GrsrJ	decreased body size	J:213055
	increased or absent threshold for auditory brainstem response	J:213055
	infertility	J:213055
	small ears	J:213055
	normal vision/eye phenotype	J:213055
Prkra^lear/Prkra^lear B6(CAST)-Prkra^lear/GrsrJ	decreased body size	J:159349
	impaired hearing	J:223062
	reduced fertility	J:223062
	small ears	J:159349
Prkra^rep/Prkra⁺ involves: C3HeB/FeJ * C57BL/6J	short nasal bone	J:185991
Prkra^rep/Prkra^rep involves: C3HeB/FeJ * C57BL/6J	abnormal temporal bone zygomatic process morphology	J:185991
	decreased body weight	J:185991
	female infertility	J:185991
	postnatal growth retardation	J:185991
	short nasal bone	J:185991
	small ears	J:185991
	small mandibular condyloid process	J:185991
	small mandibular coronoid process	J:185991
Prkra^tm1Gcs/Prkra^tm1Gcs either: B6.Cg-Prkra^tm1Gcs or (involves: C57BL/6)	abnormal external auditory canal morphology	J:108297
	abnormal middle ear morphology	J:108297
	abnormal middle ear ossicle morphology	J:108297
	abnormal outer ear morphology	J:108297
	decreased body size	J:108297
	decreased body weight	J:108297
	increased or absent threshold for auditory brainstem response	J:108297
	round snout	J:108297
	short snout	J:108297
	small ears	J:108297
	turbinate hypoplasia	J:108297
Prkra^tm1Gcs/Prkra^tm1Gcs Not Specified	abnormal neurocranium morphology	J:185991
	small interparietal bone	J:185991
	small mandibular condyloid process	J:185991
	wide cranial sutures	J:185991
Prkra^tm1Wsmay/Prkra^tm1Wsmay involves: 129S4/SvJae * C57BL/6J	embryonic lethality before implantation, complete penetrance	J:139044

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