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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Zeb2
zinc finger E-box binding homeobox 2
MGI:1344407
18 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm18(Zeb2)Jhai/Gt(ROSA)26Sor+
Tg(Tek-cre)1Ywa/0
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * C57BL/6 * CD-1 * SJL 		increased T cell derived lymphoma incidence J:263520
Gt(ROSA)26Sortm18(Zeb2)Jhai/Gt(ROSA)26Sortm18(Zeb2)Jhai
Tg(Tek-cre)1Ywa/0
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * C57BL/6 * CD-1 * SJL 		increased leukemia incidence J:263520
increased T cell derived lymphoma incidence J:263520
increased thymoma incidence J:263520
Rr253em2Kmm/Rr253em2Kmm
Zeb2tm2.1Yhi/Zeb2tm2.1Yhi
Not Specified 		normal embryo phenotype J:316113
Zeb1tm2Yhi/Zeb1+
Zeb2tm1.2Yhi/Zeb2+
involves: 129S1/Sv * 129X1/SvJ * ICR 		decreased body size J:108819
vagina atresia J:108819
Zeb1tm2Yhi/Zeb1tm2Yhi
Zeb2tm1.1Yhi/Zeb2tm1.1Yhi
Tg(Zp3-cre)3Mrt/0
involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR 		abnormal neural plate morphology J:108819
abnormal neural tube morphology J:108819
abnormal somite development J:108819
decreased somite size J:108819
embryonic growth arrest J:108819
embryonic lethality between somite formation and embryo turning, complete penetrance J:108819
failure of initiation of embryo turning J:108819
open neural tube J:108819
Zeb1tm2Yhi/Zeb1tm2Yhi
Zeb2tm1.2Yhi/Zeb2+
involves: 129S1/Sv * 129X1/SvJ * FVB/N * ICR 		abnormal brain ventricle morphology J:108819
embryonic lethality during organogenesis J:108819
exencephaly J:108819
midline facial cleft J:108819
open neural tube J:108819
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory