Ldb3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ldb3
LIM domain binding 3
MGI:1344412

49 phenotypes from 7 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ldb3^tm1Chen/Ldb3^tm1Chen involves: 129S1/Sv * 129X1/SvJ * Black Swiss	abnormal myocardium layer morphology	J:72799
	abnormal skeletal muscle morphology	J:72799
	cyanosis	J:72799
	dilated heart left ventricle	J:72799
	dilated heart right ventricle	J:72799
	dysphagia	J:72799
	heart vascular congestion	J:72799
	impaired limb coordination	J:72799
	muscle weakness	J:72799
	myopathy	J:72799
	neonatal lethality, incomplete penetrance	J:72799
	postnatal lethality, complete penetrance	J:72799
	respiratory distress	J:72799
Ldb3^{tm2b(EUCOMM)Hmgu}/Ldb3⁺ C57BL/6N-Ldb3^{tm2b(EUCOMM)Hmgu}/Bay	decreased locomotor activity	J:211773
	enlarged kidney	J:211773
	increased basophil cell number	J:211773
	increased large unstained cell number	J:211773
	prolonged QRS complex duration	J:211773
	small seminal vesicle	J:211773
Ldb3^{tm2b(EUCOMM)Hmgu}/Ldb3^{tm2b(EUCOMM)Hmgu} C57BL/6N-Ldb3^{tm2b(EUCOMM)Hmgu}/Bay	preweaning lethality, complete penetrance	J:211773
Ldb3^tm2Chen/Ldb3^tm2Chen involves: 129S1/Sv * 129X1/SvJ * Black Swiss	abnormal skeletal muscle morphology	J:82141
	cardiac fibrosis	J:82141
	decreased body weight	J:82141
	increased variability of skeletal muscle fiber size	J:82141
	myopathy	J:82141
	postnatal lethality, incomplete penetrance	J:82141
	skeletal muscle fiber atrophy	J:82141
Ldb3^tm3Chen/Ldb3^tm3Chen involves: 129S1/Sv * 129X1/SvJ * Black Swiss	abnormal skeletal muscle morphology	J:82141
	cardiac fibrosis	J:82141
	decreased body weight	J:82141
	increased variability of skeletal muscle fiber size	J:82141
	myopathy	J:82141
	postnatal lethality, incomplete penetrance	J:82141
	skeletal muscle fiber atrophy	J:82141
Ldb3^tm4Chen/Ldb3^tm4Chen A1cf^{Tg(Myh6-cre/Esr1)1Jmk}/A1cf⁺ involves: 129S1/Sv 129X1/SvJ * Black Swiss * FVB/N	abnormal cardiovascular system physiology	J:144739
	dilated cardiomyopathy	J:144739
	dilated heart left ventricle	J:144739
	dilated heart right ventricle	J:144739
	enlarged heart	J:144739
	premature death	J:144739
Ldb3^tm4Chen/Ldb3^tm4Chen Myl2^tm1(cre)Krc/Myl2⁺ involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * Black Swiss	abnormal heart left ventricle morphology	J:144739
	abnormal heart right ventricle morphology	J:144739
	abnormal heart ventricle morphology	J:144739
	abnormal myocardial fiber morphology	J:144739
	atrioventricular block	J:144739
	cardiac hypertrophy	J:144739
	dilated cardiomyopathy	J:144739
	enlarged heart	J:144739
	increased heart weight	J:144739
	premature death	J:144739
	thin interventricular septum	J:144739
	thin ventricular wall	J:144739
Ldb3^tm5.2Chen/Ldb3^tm5.2Chen involves: 129/Sv * Black Swiss * C57BL/6 * SJL	normal cardiovascular system phenotype	J:170494
Ldb3^tm6.2Chen/Ldb3^tm6.2Chen involves: 129/Sv * Black Swiss * C57BL/6 * SJL	abnormal heart morphology	J:170494
	abnormal Z line morphology	J:170494
	cardiac fibrosis	J:170494
	decreased body size	J:170494
	decreased cardiac muscle contractility	J:170494
	decreased heart left ventricle posterior wall thickness	J:170494
	dilated cardiomyopathy	J:170494
	increased heart left ventricle size	J:170494
	increased heart left ventricle weight	J:170494
	increased heart right ventricle size	J:170494
	increased heart weight	J:170494
	increased response of heart to induced stress	J:170494
	postnatal growth retardation	J:170494
	postnatal lethality, incomplete penetrance	J:170494
	premature death	J:170494

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