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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Osr1
odd-skipped related transcription factor 1
MGI:1344424
41 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Osr1tm1(EGFP/cre/ERT2)Amc/Osr1+
Not Specified
no abnormal phenotype detected J:143306
Osr1tm1Jian/Osr1tm1Jian
either: (involves: 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * ICR)
abnormal blood circulation J:104942
abnormal fetal atrioventricular canal morphology J:104942
abnormal interatrial septum morphology J:104942
abnormal interventricular septum morphology J:104942
abnormal kidney development J:104942
abnormal lung morphology J:104942
abnormal mesonephros morphology J:104942
abnormal metanephric mesenchyme morphology J:104942
abnormal nephrogenic mesenchyme morphogenesis J:104942
abnormal pericardium development J:104942
abnormal vein morphology J:104942
abnormal Wolffian duct morphology J:104942
absent adrenal gland J:104942
absent metanephros J:104942
absent ovary J:104942
absent testes J:104942
absent ureteric bud J:104942
absent vitelline blood vessels J:104942
agonadal J:104942
common atrium J:104942
dilated heart atrium J:104942
embryonic lethality during organogenesis, incomplete penetrance J:104942
gonadal ridge hypoplasia J:104942
hydrops fetalis J:104942
increased kidney apoptosis J:104942
lethality throughout fetal growth and development, complete penetrance J:104942
rudimentary Wolffian ducts J:104942
Osr1tm1Jian/Osr1tm1Jian
involves: 129S1/Sv
abnormal mesonephric mesenchyme morphology J:117734
abnormal mesonephros morphology J:117734
abnormal metanephric mesenchyme morphology J:117734
abnormal Wolffian duct morphology J:117734
absent metanephric mesenchyme J:117734
absent metanephros J:117734
absent ureteric bud J:117734
increased metanephric mesenchyme apoptosis J:117734
rudimentary Wolffian ducts J:117734
Osr1tm2.1Jian/Osr1tm2.1Jian
involves: 129S1/Sv
abnormal cardiovascular system morphology J:171478
abnormal reproductive system morphology J:171478
abnormal survival J:171478
Osr1tm2.1Jian/Osr1tm2.1Jian
involves: 129S1/Sv * FVB/N
abnormal epicardium morphology J:172133
abnormal forelimb bud morphology J:172133
edema J:172133
embryonic growth arrest J:172133
embryonic lethality during organogenesis, complete penetrance J:172133
hemorrhage J:172133
Osr1tm2.2Jian/Osr1tm2.2Jian
involves: 129S1/Sv * 129S4/SvJaeSor
no abnormal phenotype detected J:172133
Osr1tm2Jian/Osr1tm2Jian
Tg(Prrx1-cre)1Cjt/0
involves: 129S1/Sv * C57BL/6J * SJL/J
normal skeleton phenotype J:171478

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory