Pglyrp1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pglyrp1
peptidoglycan recognition protein 1
MGI:1345092

17 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pglyrp1^tm1.1Lky/Pglyrp1^tm1.1Lky B6.129S4-Pglyrp1^tm1.1Lky	abnormal neutrophil physiology	J:171412
Pglyrp1^tm1.1Lky/Pglyrp1^tm1.1Lky B6.129S4-Pglyrp1^tm1.1Lky	increased susceptibility to bacterial infection	J:171412
Pglyrp1^tm1Rdz/Pglyrp1^tm1Rdz C.129S-Pglyrp1^tm1Rdz	increased susceptibility to induced arthritis	J:178054
Pglyrp1^tm1Rdz/Pglyrp1^tm1Rdz involves: 129S5/SvEvBrd	abnormal neutrophil physiology	J:84680
	impaired granulocyte bactericidal activity	J:84680
	increased susceptibility to bacterial infection	J:84680
	increased susceptibility to bacterial infection induced morbidity/mortality	J:84680
Pglyrp1^tm1Rdz/Pglyrp1^tm1Rdz involves: 129S5/SvEvBrd * BALB/c	abnormal chemokine secretion	J:178053
	abnormal crypts of Lieberkuhn morphology	J:178053
	abnormal gut flora balance	J:178053
	abnormal intestinal epithelium morphology	J:178053
	abnormal intestinal goblet cell morphology	J:178053
	abnormal intestinal mucosa morphology	J:178053
	gastrointestinal hemorrhage	J:178053
	increased interleukin-6 secretion	J:178053
	increased susceptibility to induced colitis	J:178053
	increased susceptibility to xenobiotic induced morbidity/mortality	J:178053
	intestinal ulcer	J:178053
	weight loss	J:178053

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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