Spry1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Spry1
sprouty RTK signaling antagonist 1
MGI:1345139

17 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Spry1^tm1.1Jdli/Spry1^tm1.1Jdli involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N	abnormal branching involved in ureteric bud morphogenesis	J:96485
	abnormal kidney morphology	J:96485
	abnormal nephrogenic zone morphology	J:96485
	abnormal ureter development	J:96485
	abnormal ureter morphology	J:96485
	abnormal ureteric bud morphology	J:96485
	abnormal ureteric bud tip morphology	J:96485
	abnormal ureteric bud trunk morphology	J:96485
	blind ureter	J:96485
	ectopic ureter	J:96485
	ectopic ureteric bud	J:96485
	fused kidneys	J:96485
	hydroureter	J:96485
	kidney cyst	J:96485
	postnatal lethality, incomplete penetrance	J:96485
	premature death	J:96485
Spry1^tm1Jdli/Spry1^tm1Jdli involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	no abnormal phenotype detected	J:96485
Spry1^tm1Jdli/Spry1^tm1Jdli Tg(Hoxb7-cre)13Amc/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal kidney morphology	J:96485
	abnormal ureter morphology	J:96485
	ectopic ureter	J:96485
	hydroureter	J:96485

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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