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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Spry1
sprouty RTK signaling antagonist 1
MGI:1345139
7 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gdnftm1(cre/ERT2)Cos/Gdnf+
Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+
Spry1tm1.1Jdli/Spry1+
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J 		small kidney J:206853
Gdnftm1Bbd/Gdnf+
Spry1tm1.1Jdli/Spry1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		normal renal/urinary system phenotype J:206853
Gdnftm2Bbd/Gdnf+
Spry1tm1.1Jdli/Spry1tm1.1Jdli
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * FVB/N 		abnormal kidney development J:96485
Itga8tm1Lfr/Itga8tm1Lfr
Spry1tm1.1Jdli/Spry1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		absent kidney J:122519
Itga8tm1Lfr/Itga8tm1Lfr
Spry1tm1.1Jdli/Spry1tm1.1Jdli
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		normal renal/urinary system phenotype J:122519
Ptentm2.1Ppp/Pten+
Spry1tm1Jdli/Spry1tm1.1Jdli
Spry2tm1Mrt/Spry2tm1.1Mrt
Tg(Osr1-cre)4Mrt/0
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N 		increased prostate gland tumor incidence J:192348
increased prostate intraepithelial neoplasia incidence J:192348
Spry1tm1Jdli/Spry1tm1.1Jdli
Spry2tm1Mrt/Spry2tm1.1Mrt
Tg(Osr1-cre)4Mrt/0
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N 		increased prostate intraepithelial neoplasia incidence J:192348
prostate gland epithelial hyperplasia J:192348
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory