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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Scn11a
sodium channel, voltage-gated, type XI, alpha
MGI:1345149
14 phenotypes from 10 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Scn11aem1(IMPC)H/Scn11aem1(IMPC)H
C57BL/6NTac-Scn11aem1(IMPC)H/H 		decreased lean body mass J:211773
Scn11aem1Akoi/Scn11a+
involves: C57BL/6 		abnormal action potential J:268684
abnormal nervous system electrophysiology J:268684
abnormal thermal nociception J:268684
decreased thermal nociceptive threshold J:268684
Scn11aem2Akoi/Scn11a+
involves: C57BL/6NCrSlc 		abnormal action potential J:268091
abnormal nervous system electrophysiology J:268091
Scn11aem3Akoi/Scn11a+
involves: C57BL/6NCrSlc 		abnormal action potential J:268091
abnormal nervous system electrophysiology J:268091
Scn11atm1.1Ikth/Scn11a+
involves: 129 * BALB/c * C57BL/6 		abnormal action potential J:206848
abnormal afterhyperpolarization J:206848
abnormal channel response J:206848
abnormal miniature excitatory postsynaptic currents J:206848
abnormal nervous system electrophysiology J:206848
abnormal nociception after inflammation J:206848
normal integument phenotype J:206848
skin lesions J:206848
Scn11atm1Dgen/Scn11a+
involves: 129P2/OlaHsd * C57BL/6 		abnormal nociception after inflammation J:99870
Scn11atm1Dgen/Scn11atm1Dgen
involves: 129P2/OlaHsd * C57BL/6 		abnormal nociception after inflammation J:99870
Scn11atm1Gsk/Scn11atm1Gsk
involves: 129P2/OlaHsd * C57BL/6 		abnormal single cell response J:216497
Scn11atm1Lex/Scn11atm1Lex
involves: 129S5/SvEvBrd * C57BL/6 		abnormal mechanical nociception J:157013
abnormal nociception after inflammation J:157013
abnormal pain threshold J:157013
Scn11atm1Mdba/Scn11atm1.1Ikth
involves: 129 * BALB/c * C57BL/6 		abnormal channel response J:206848
abnormal nervous system electrophysiology J:206848
Scn11atm1Mdba/Scn11atm1Mdba
involves: C57BL/6 		abnormal nervous system electrophysiology J:141209
Scn11atm1Mdba/Scn11atm1Mdba
Not Specified 		abnormal action potential J:206848
abnormal nervous system electrophysiology J:206848
Scn11atm1Wlf/Scn11atm1Wlf
B6.Cg-Scn11atm1Wlf 		abnormal nociception after inflammation J:116768
abnormal single cell response J:116768
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory