Slc11a1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc11a1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
MGI:1345275

8 phenotypes from 4 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc11a1^em1(IMPC)Mbp/Slc11a1^em1(IMPC)Mbp C57BL/6N-Slc11a1^em1(IMPC)Mbp/MbpMmucd	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	decreased lymphocyte cell number	J:211773
	enlarged spleen	J:211773
	increased neutrophil cell number	J:211773
Slc11a1^r/Slc11a1^r 129/Sv	decreased susceptibility to bacterial infection	J:81412
Slc11a1^r/Slc11a1^r C3H/HeJ-Slc11a1^r	decreased susceptibility to bacterial infection	J:35004
Slc11a1^r/Slc11a1^s (129/Sv x BALB/c)F1	decreased susceptibility to bacterial infection	J:28278
Slc11a1^s/Slc11a1^r (129/Sv x C57BL/6J)F1	abnormal susceptibility to bacterial infection	J:81412
Slc11a1^s/Slc11a1^s BALB/c	increased susceptibility to bacterial infection	J:28278
Slc11a1^s/Slc11a1^s C57BL/6J	increased susceptibility to bacterial infection	J:81412
Slc11a1^tm1Mcg/Slc11a1^s involves: 129S4/SvJae * BALB/c	increased susceptibility to bacterial infection	J:28278
Slc11a1^tm1Mcg/Slc11a1^tm1Mcg involves: 129S4/SvJae * BALB/c	increased susceptibility to bacterial infection	J:28278

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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