Ddr2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ddr2
discoidin domain receptor family, member 2
MGI:1345277

53 phenotypes from 6 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ddr2^m1Anu/Ddr2^m1Anu either: C57BL/6JSfdAnu-Ddr2^m1Anu or (involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd * NOD/ShiLt)	decreased body size	J:104190
	short face	J:104190
Ddr2^slie/Ddr2^slie BKSChpLt.Cg-Tg(Ins2-Cpe)1Lt Cpe^fat/LtJng	abnormal Sertoli cell morphology	J:134371
	abnormal spermatid morphology	J:134371
	abnormal spermatogonia morphology	J:134371
	abnormal vagina orifice morphology	J:134371
	absent corpus luteum	J:134371
	anovulation	J:134371
	decreased blood urea nitrogen level	J:134371
	decreased bone mineral content	J:134371
	decreased circulating estradiol level	J:134371
	decreased circulating progesterone level	J:134371
	decreased circulating testosterone level	J:134371
	decreased percent body fat/body weight	J:134371
	decreased survivor rate	J:134371
	disproportionate dwarf	J:134371
	exophthalmos	J:134371
	failure of superovulation	J:134371
	female infertility	J:134371
	increased circulating glucose level	J:134371
	increased lean body mass	J:134371
	Leydig cell atrophy	J:134371
	reduced male fertility	J:134371
	short snout	J:134371
	slow postnatal weight gain	J:134371
	small pituitary gland	J:134371
Ddr2^{tm1.1(cre/Esr1)Rcow}/Ddr2^{tm1.1(cre/Esr1)Rcow} involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cardiac muscle relaxation	J:214642
	abnormal cranium morphology	J:214642
	abnormal heart echocardiography feature	J:214642
	abnormal heart left ventricle pressure	J:214642
	abnormal heart morphology	J:214642
	decreased body weight	J:214642
	decreased cardiac muscle contractility	J:214642
	decreased collagen level	J:214642
	decreased heart weight	J:214642
	decreased myocardial fiber size	J:214642
	flattened snout	J:214642
	infertility	J:214642
	pregnancy-related premature death	J:214642
	reduced fertility	J:214642
	short limbs	J:214642
	short tibia	J:214642
	small heart	J:214642
Ddr2^{tm1a(EUCOMM)Wtsi}/Ddr2^{tm1a(EUCOMM)Wtsi} FVB.B6N-Ddr2^{tm1a(EUCOMM)Wtsi}	decreased body size	J:236031
	normal endocrine/exocrine gland phenotype	J:236031
	infertility	J:236031
Ddr2^{tm1b(EUCOMM)Wtsi}/Ddr2^{tm1b(EUCOMM)Wtsi} FVB.B6N(Cg)-Ddr2^{tm1b(EUCOMM)Wtsi}	decreased body size	J:236031
	normal endocrine/exocrine gland phenotype	J:236031
	infertility	J:236031
Ddr2^tm1Kln/Ddr2^tm1Kln involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cranium morphology	J:123719
	abnormal epiphyseal plate morphology	J:74580
	abnormal nasal bone morphology	J:123719
	abnormal neurocranium morphology	J:123719
	decreased body size	J:74580
	decreased body weight	J:74580
	decreased cell proliferation	J:74580
	decreased cranium height	J:123719
	decreased length of long bones	J:74580
	delayed wound healing	J:74580
	disproportionate dwarf	J:74580
	postnatal growth retardation	J:74580
	short snout	J:74580
	small cranium	J:74580, J:123719

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