Tlk2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tlk2
tousled-like kinase 2 (Arabidopsis)
MGI:1346023

18 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tlk2^em1(IMPC)Bay/Tlk2⁺ C57BL/6N-Tlk2^em1(IMPC)Bay/BayMmucd	abnormal bone structure	J:211773
Tlk2^em1(IMPC)Bay/Tlk2⁺ C57BL/6N-Tlk2^em1(IMPC)Bay/BayMmucd	increased bone mineral content	J:211773
Tlk2^em1(IMPC)Bay/Tlk2^em1(IMPC)Bay C57BL/6N-Tlk2^em1(IMPC)Bay/BayMmucd	abnormal embryo turning	J:211773
	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773
Tlk2^tm1.1Strc/Tlk2^tm1.2Strc Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ involves: 129S/SvEv * C3H * C57BL/6	no abnormal phenotype detected	J:268910
Tlk2^tm1.2Strc/Tlk2^tm1.2Strc involves: 129S/SvEv * C3H * C57BL/6	abnormal placenta labyrinth morphology	J:268910
	abnormal placenta vasculature	J:268910
	abnormal syncytiotrophoblast morphology	J:268910
	abnormal trophoblast layer morphology	J:268910
	decreased spongiotrophoblast cell number	J:268910
	decreased trophoblast giant cell number	J:268910
	disorganized placental labyrinth	J:268910
	small placenta	J:268910
Tlk2^tm1Strc/Tlk2^tm1Strc Not Specified	anemia	J:268910
	decreased embryo size	J:268910
	lethality throughout fetal growth and development, complete penetrance	J:268910
	pale placenta	J:268910
	small placenta	J:268910

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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