Pin1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pin1
peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1
MGI:1346036

13 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pin1^tm1Tuc/Pin1^tm1Tuc B6.129P2-Pin1^tm1Tuc	abnormal ovarian follicle number	J:83663
	decreased litter size	J:83663
	decreased primordial germ cell number	J:83663
	decreased primordial germ cell proliferation	J:83663
	reduced female fertility	J:83663
	reduced male fertility	J:83663
Pin1^tm1Tuc/Pin1^tm1Tuc involves: 129 * 129P2/OlaHsd * C57BL/6	amyloid beta deposits	J:107132
Pin1^tm1Tuc/Pin1^tm1Tuc involves: 129P2/OlaHsd * C57BL/6	abnormal mammary gland growth during pregnancy	J:74508
	azoospermia	J:74508
	decreased body weight	J:74508
	decreased testis weight	J:74508
	increased susceptibility to age-related retinal degeneration	J:74508
	seminiferous tubule degeneration	J:74508

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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