Aplnr Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Aplnr
apelin receptor
MGI:1346086

24 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Aplnr^{tm1.1(KOMP)Vlcg}/Aplnr⁺ C57BL/6N-Aplnr^{tm1.1(KOMP)Vlcg}/Ucd	decreased prepulse inhibition	J:211773
Aplnr^{tm1.1(KOMP)Vlcg}/Aplnr^{tm1.1(KOMP)Vlcg} C57BL/6N-Aplnr^{tm1.1(KOMP)Vlcg}/Ucd	abnormal epididymis morphology	J:211773
	abnormal eye morphology	J:211773
	abnormal kidney morphology	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Aplnr^tm1.1Path/Aplnr^tm1.1Path Not Specified	abnormal vein morphology	J:227456
	heart right ventricle hypertrophy	J:227456
	increased pulmonary artery pressure	J:227456
	pulmonary edema	J:227456
	venoocclusion	J:227456
Aplnr^tm1.1Tq/Aplnr⁺ C57BL/6-Aplnr^tm1.1Tq	abnormal maternal behavior	J:154303
Aplnr^tm1.1Tq/Aplnr⁺ C57BL/6-Aplnr^tm1.1Tq	decreased litter size	J:154303
Aplnr^tm1.1Tq/Aplnr^tm1.1Tq C57BL/6-Aplnr^tm1.1Tq	abnormal heart development	J:154303
	abnormal maternal behavior	J:154303
	abnormal myocardial fiber physiology	J:154303
	decreased cardiac muscle contractility	J:154303
	embryonic growth arrest	J:154303
	impaired exercise endurance	J:154303
	prenatal lethality, incomplete penetrance	J:154303
Aplnr^tm1Afu/Aplnr^tm1Afu involves: C57BL/6 * CBA	abnormal systemic arterial blood pressure	J:91164
Aplnr^tm1Afu/Aplnr^tm1Afu involves: C57BL/6 * CBA	normal cardiovascular system phenotype	J:91164
Aplnr^tm1Dgen/Aplnr^tm1Dgen involves: 129X1/SvJ * C57BL/6J	abnormal urination	J:186909
	decreased body weight	J:186909
	decreased fluid intake	J:186909
	decreased urine osmolality	J:186909
	preweaning lethality, incomplete penetrance	J:186909
Aplnr^tm1Path/Aplnr^tm1Path Tg(Kdr-cre)#Brei/0 involves: C57BL/6	abnormal vein morphology	J:227456
	heart right ventricle hypertrophy	J:227456
	increased pulmonary artery pressure	J:227456
	pulmonary edema	J:227456
	venoocclusion	J:227456

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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